Almost famous: Human adenoviruses (and what they have taught us about cancer) [PDF]
Tumour Virus Research, 2021 Papillomaviruses, polyomaviruses and adenoviruses are collectively categorized as the small DNA tumour viruses. Notably, human adenoviruses were the first human viruses demonstrated to be able to cause cancer, albeit in non-human animal models.
Tanner M. Tessier +5 more
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Molecular characterisation of human adenoviruses associated with respiratory infections in Uganda [PDF]
BMC Infectious Diseases, 2023 Human adenoviruses (HAdV) are a diverse group of viruses causing a broad range of infections of the respiratory, urogenital and gastrointestinal tracts and keratoconjunctivitis.
Qouilazoni A. Ukuli +9 more
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Human adenoviruses in children with gastroenteritis: a systematic review and meta-analysis [PDF]
BMC Infectious DiseasesPurpose Human adenoviruses (HAdVs) have always been suggested as one of the main causes of gastroenteritis in children. However, no comprehensive report on the global epidemiology of these viruses in pediatric gastroenteritis is available.
Pegah Khales +10 more
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Molecular evolution of human adenoviruses [PDF]
Scientific Reports, 2013 The recent emergence of highly virulent human adenoviruses (HAdVs) with new tissue tropisms underscores the need to determine their ontogeny. Here we report complete high quality genome sequences and analyses for all the previously unsequenced HAdV ...
Betensky, Rebecca Aubrey +11 more
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Human adenoviruses role in ophthalmic pterygium formation [PDF]
Jundishapur Journal of Microbiology, 2015 Background: Ophthalmic pterygium is a common benign lesion of unknown origin and the pathogenesis might be vision-threatening. This problem is often associated with exposure to solar light. Recent evidence suggests that potentially oncogenic viruses such
Bazouri, M. +5 more
core +5 more sources
Human adenoviruses: A suspect behind the outbreak of acute hepatitis in children amid the COVID-19 pandemic [PDF]
Cell Insight, 2022 As of 10 May 2022, at least 450 cases of pediatric patients with acute hepatitis of unknown cause have been reported worldwide. Human adenoviruses (HAdVs) have been detected in at least 74 cases, including the F type HAdV41 in 18 cases, which indicates ...
Hongyun Wang +8 more
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Serotype Chimeric Human Adenoviruses for Cancer GeneTherapy [PDF]
Viruses, 2010 Cancer gene therapy consists of numerous approaches where the common denominator is utilization of vectors for achieving therapeutic effect. A particularly potent embodiment of the approach is virotherapy, in which the replication potential of an ...
Akseli Hemminki, Tuuli Ranki
doaj +4 more sources
Anti-Viral Drugs for Human Adenoviruses
Pharmaceuticals, 2010 There are many stages in the development of a new drug for viral infection and such processes are even further complicated for adenovirus by the fact that there are at least 51 serotypes, forming six distinct groups (A–F), with different degree of ...
Chor Wing Sing, Mary Miu Yee Waye
doaj +2 more sources
Evolution of Human Adenoviruses, a Double-Stranded DNA Viral Pathogen Documented Through Genomics and Bioinformatics and Viewed Through a Web Resource Database [PDF]
VirusesHuman adenoviruses (HAdVs) remain prominent global human pathogens, particularly in dense, crowded populations. The advent of genomic and bioinformatic tools allows for high-resolution means to identify, characterize, and understand these pathogens ...
Katayoon Dadkhah +4 more
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Human Adenoviruses, Cholesterol Trafficking, and NF-κB Signaling. [PDF]
J Immunol Sci, 2018 The interplay between viruses and host factors regulating inflammatory or cytotoxic responses directed against infected cells is well documented. Viruses have evolved a wide array of mechanisms that strike a balance between the elimination of virus and immune-mediated tissue injury by antiviral immune responses.
Cianciola NL, Carlin CR.
europepmc +3 more sources