Results 51 to 60 of about 9,289,046 (328)

Inhibition of tumor necrosis factor α–stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase [PDF]

, 2008
<b>Objective</b>— Proatherosclerotic adhesion of leukocytes to the endothelium is attenuated by NO. As AMP-activated protein kinase (AMPK) regulates endothelial NO synthesis, we investigated the modulation of adhesion to cultured human aortic
Ewart, M-A., Kohlhaas, C.F., Salt, I.P.
core   +1 more source

Pyrogenicity of human adenoviruses

Journal of General Virology, 2000
High doses (>1·56×107 p.f.u.) of purified preparations of human adenovirus types 3, 5 and 8 exhibited definite pyrogenic activity when injected intravenously into rabbits. Complete pyrogenic tolerance was obtained not only with homologous types but also with heterologous types of adenovirus.
openaire   +2 more sources

Challenges in management of epidemic keratoconjunctivitis with emerging recombinant human adenoviruses.

Journal of Clinical Virology, 2019
Adenoviral epidemic keratoconjunctivitis (EKC) presents as severe conjunctival inflammations involving the cornea that can lead to the development of corneal opacities and blurred vision, which can persist for months.
G. González, N. Yawata, K. Aoki, N. Kitaichi   +3 more
semanticscholar   +1 more source

Retargeted adenoviruses for radiation-guided gene delivery [PDF]

, 2016
The combination of radiation with radiosensitizing gene delivery or oncolytic viruses promises to provide an advantage that could improve the therapeutic results for glioblastoma. X-rays can induce significant molecular changes in cancer cells.
A Beetz, AP Patel, BL Davidson, C Roller, Cancer Genome Atlas Research Network, D E Hallahan, DA Boothman, DA Reardon, DA Spencer, DE Hallahan, DY Dadey, F Tameire, G Bajocchi, H Hsu, H Li, H Yan, HO McCarthy, JJ Mezhir, K Daino, L N Kaliberova, LM Hendershot, M Gonzalez-Gronow, M Hamdi, M Martin, M Westphal, MA Arap, MJ Gray, N Belousova, N Mittereder, R Datta, R Stupp, R Stupp, RJ Passarella, RR Weichselbaum, S A Kaliberov, S Akli, S Mittal, S Parisi, S Takahashi, SA Kaliberov, SC Noureddini, SL Eck, SS Talibi, T Ichikawa, TA Ajith, TC He, Ulasov IV, V Kapoor, VN Krasnykh, WL Blalock, WW Zhang, X Xing, Y Touchefeu, Y Zhang, YL Tsai   +54 more
core   +2 more sources

Sequence homology between avian and human adenoviruses [PDF]

Journal of Virology, 1982
Studies of hybridization between fowl adenovirus type 1 (chicken embryo lethal orphan virus) DNA and human adenovirus type 2 DNA revealed two short but distinct regions which cross-hybridized under stringent conditions. One of the homologous regions was located between map positions 18.1 and 19.3 and did not correspond to any gene recognized so far ...
P, Aleström, A, Stenlund, P, Li, A, Bellett, U, Pettersson   +4 more
openaire   +2 more sources

Antiviral activity of Hellenia speciosa (J. Koenig) S.R. Dutta rhizome metabolites against human adenovirus: insights from molecular docking and in vitro studies

Frontiers in Pharmacology
BackgroundHuman adenoviruses (HAdVs) cause a wide range of clinical diseases, yet effective antiviral therapies remain limited. Natural products, particularly medicinal plants, offer potential sources of antiviral agents.PurposeThis study aimed to ...
Sara Alnhhas, Thamer Bouback, Abdulaziz Albeshri, Tasneem Alsahafi, Faisal Al-Sarraj, Faten A. Al-Sulaimany, Mohamed Ali, Yassmin Moatasim, Omnia Kutkat, Mohamed Gaballah, Raied Badierah, Eman O. Taibah, Yaaser Q. Almulaiky, Yaaser Q. Almulaiky, Fawaz Al-Zughaibi, Mohammed Mufrrih, Mohammed Mufrrih, Saleh M. Al-Maaqar, Saleh M. Al-Maaqar, Suzan M. Fathuldeen   +19 more
doaj   +1 more source

Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells

Journal for ImmunoTherapy of Cancer, 2018
Background Oncolytic viruses are currently experiencing accelerated development in several laboratories worldwide, with some forty-seven clinical trials currently recruiting.
Janet Lei, Egon J. Jacobus, William K. Taverner, Kerry D. Fisher, Silvio Hemmi, Katy West, Lorna Slater, Fred Lilley, Alice Brown, Brian Champion, Margaret R. Duffy, Len W. Seymour   +11 more
doaj   +1 more source

Construction and characterization of recombinant human adenovirus type 5 expressing foot-and-mouth disease virus capsid proteins of Indian vaccine strain, O/IND/R2/75 [PDF]

Veterinary World, 2015
Aim: Generation of recombinant human adenovirus type 5 expressing foot-and-mouth disease virus (FMDV) capsid protein genes along with full-length 2B, 3B and 3Cpro and its characterization.
Ramesh Kumar, B. P. Sreenivasa , R. P. Tamilselvan   +2 more
doaj   +1 more source

Viruses associated with pneumonia in adults. [PDF]

, 2012
Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source