Results 111 to 120 of about 2,152,983 (311)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Adult literacy and economic growth [PDF]
Developed countries, including New Zealand, used to consider their populations wholly literate, in the sense that almost all adults could read and write.
Grant Johnston
core
Operative cystoscopy in the neonatal period
La Pediatria Medica e Chirurgica, 2016 Aim of the study is to report the experience in the last three years about endourological treatment of newborns affected by genito- and urinary malformation, implying critical urinary tract dilatation and bladder mass requiring a neonatal operative ...
Salvatore Arena +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Motivational strategies and their applications to the educational needs of adult learners at institutions of higher education [PDF]
, 2003 Plan BAdult education and what motivates adult learners to come back to schools is not a new issue in the field of education. Although, in recent years more and more attention is directed towards adult learners and their motivation to learn, their needs ...
Hubbard, Audra
core
Human-AI Engineering for Adults
The engineering of reliable and trustworthy AI systems needs to mature. While facing unprecedented challenges, there is much to be learned from other engineering disciplines. We focus on the five pillars of (i) Models & Explanations, (ii) Causality & Grounding, (iii) Modularity & Compositionality, (iv) Human Agency & Oversight, and (v ...
André Meyer-Vitali, Wico Mulder
openaire +2 more sources
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
International Journal of Educational Research OpenDespite the growing population of non-traditional (mature) students in online learning programmes in universities across the world, less is known about the online learning readiness of this unique category of students.
David Addae, Ellen Abakah, Delali Amuzu
doaj +1 more source