Results 51 to 60 of about 10,333 (209)

Kynurenine Pathway Activation in Human African Trypanosomiasis [PDF]

Journal of Infectious Diseases, 2016
The kynurenine pathway of tryptophan oxidation is associated with central nervous system (CNS) inflammatory pathways. Inhibition of this pathway ameliorates CNS inflammation in rodent models of the late (meningoencephalitic) stage of human African trypanosomiasis (HAT).
Sternberg, Jeremy M., Forrest, Caroline M., Dalton, R. Neil, Turner, Charles, Rodgers, Jean, Stone, Trevor W., Kennedy, Peter G.E.   +6 more
openaire   +6 more sources

Pandemic Prevention Paradigms: Understanding Global Health Governance

Public Health Challenges, Volume 4, Issue 2, June 2025.
One Health is an emerging area of integrative studies and interventions aimed at preventing zoonotic diseases by addressing human, animal, and environmental interactions. A fundamental aspect of the concept is understanding how these interactions influence health outcomes among humans, animals, and ecosystems. Developed initially to respond to the need
Soheil Sadr, Cinzia Santucciu, Valentina Chisu, Narges Lotfalizadeh, Shakiba Nazemian, Negin Esfandiari, Ashkan Hajjafari, Helia Sepahvand, Abbas Rahdar, Sadanand Pandey, Hassan Borji   +10 more
wiley   +1 more source

Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China

International Journal of Infectious Diseases, 2019
We report the first imported case in China of human African trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense, in a sailor returning from Gabon in 2014.
Nian Chen, Ke Jin, Jingjing Xu, Jianfu Zhang, Yali Weng   +4 more
doaj  

Towards the Atlas of human African trypanosomiasis

International Journal of Health Geographics, 2009
Background Updated, accurate and comprehensive information on the distribution of human African trypanosomiasis (HAT), also known as sleeping sickness, is critically important to plan and monitor control activities.
Mattioli Raffaele C, Ruiz José A, Diarra Abdoulaye, Fèvre Eric M, Franco José R, Paone Massimo, Cecchi Giuliano, Simarro Pere P   +7 more
doaj   +1 more source

Accelerating towards human African trypanosomiasis elimination: Issues and opportunities

Journal of Vector Borne Diseases, 2020
Human African trypanosomiasis (HAT) has been an alarming global public health issue. The disease affects mainly poor and marginalized people in low-resource settings and is caused by two subspecies of haemoflagellate parasite, Trypanosoma brucei and ...
Kingsley Uchenna Ozioko, Chris Ikem Okoye, Rose Nduka Obiezue, Idika Kalu Idika, Raymond Agbu Awudu, Bede Izuchukwu Ezewudo, Celestine Osita Ezea   +6 more
doaj   +1 more source

Perceived Threat of Zoonotic Infections in Abattoir Workers in the Tamale Metropolis of Ghana: An Assessment of Knowledge, Attitudes and Practices

Public Health Challenges, Volume 4, Issue 2, June 2025.
Most abattoir workers (90.2%) knew that humans can get zoonotic diseases from the animals they handle. However, some respondents believe that witchcraft (20.0%), curses (20.8%) and supernatural powers (18.0%) cause zoonotic diseases. ABSTRACT Background Abattoir workers are more prone to acquiring zoonotic diseases.
Benjamin Nuhu Tingbani, Ezekiel Kofi Vicar, Stephen Apanga, Elijah Bisuman Sambian, Samuel Tamanyian Suuk, Edmond Nakinpaak Biibantib, Williams Walana   +6 more
wiley   +1 more source

Determinants of Human African Trypanosomiasis Elimination via Paratransgenesis. [PDF]

PLoS Neglected Tropical Diseases, 2016
Human African trypanosomiasis (HAT), transmitted by tsetse flies, has historically infected hundreds of thousands of individuals annually in sub-Saharan Africa.
Jennifer A Gilbert, Jan Medlock, Jeffrey P Townsend, Serap Aksoy, Martial Ndeffo Mbah, Alison P Galvani   +5 more
doaj   +1 more source

Regulator experiences of trials during Ebola epidemics in Sierra Leone, Guinea, and the Democratic Republic of the Congo

Tropical Medicine &International Health, Volume 30, Issue 6, Page 539-546, June 2025.
Abstract Introduction During the 2014–2016 Ebola epidemic in West Africa and the Ebola outbreaks between 2018 and 2020 in the Democratic Republic of Congo, vaccines and other tools for prevention and treatment had to be taken through trials in exceptional circumstances using accelerated processes.
Kambale Kasonia, Frank Baiden, Frédéric Le Marcis, Bruno Lapika, Joel Kiyulu, Henri Kimina, Freddy Bikioli, Fanny Attas, Anthony Mansaray, Rose Burns, Elysée Nouvet, Séverine Thys, Antea Paviotti, Daniela Manno, Mukeh Kenneth Fahnbulleh, Bailah Leigh, Mohamed Samai, Brian Greenwood, Shelley Lees, Patrick Mitashi Mulopo, Deborah Watson‐Jones   +20 more
wiley   +1 more source

Risk Evaluation and Mitigation Strategies for Newly Detected Mysterious Dinga Dinga Virus Infection in Africa: A Narrative Review

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims The Dinga Dinga Virus (DDV) has emerged as a mysterious disease gripping women in Uganda, raising alarm due to its unusual and distressing “dancing” like symptoms. These symptoms, characterized by involuntary movements resembling dance, suggest possible neurological involvement, though the exact pathogen remains ...
Sabrina Sharmin, Salsabil Islam, Md. Aminul Haque, Md. Rabiul Islam   +3 more
wiley   +1 more source

Tick Species Infesting Livestock in Three Bioclimatic Areas of Senegal: Bioecology, Prevalence of Tick Infestation, Associated Categorical Factors and Crimean‐Congo Haemorrhagic Fever Virus Infection

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
Ticks were collected between October 2020 and November 2022, from cattle, goats and sheep in the Sahelian, Sudano‐Sahelian and Sudanian zones, and tested for CCHFV infection. A total of 3632 animals were examined and 35.3% (95% CI: 33.8–36.9) found tick‐infested.
Aliou Khoule, Déthié Ngom, Mouhamet Faye, Ousseynou Sene, Aminata Badji, Elhadji Ndiaye, Gamou Fall, Ibrahima Dia, Mawlouth Diallo, Diawo Diallo   +9 more
wiley   +1 more source