Results 121 to 130 of about 5,187,370 (343)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Race-Based Social Rejection and Mental Health: The Role of Racial Identity

open access: yesTrauma Care
Background and Introduction: Race-based social rejection has been found to predict post-traumatic stress and depression symptoms, consistent with previous studies that have shown the negative mental health effects of racism, as well as social rejection ...
Dorothy Chin   +5 more
doaj   +1 more source

Key role of PIN1 in telomere maintenance and oncogenic behavior in a human glioblastoma model

open access: bronze, 2023
Julián Maggio   +6 more
openalex   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Emotion expression in human punishment behavior [PDF]

open access: yes
Evolutionary theory reveals that punishment is effective in promoting cooperation and maintaining social norms. Although it is accepted that emotions are connected to punishment decisions, there remains substantial debate over why humans use costly ...
Daniel Houser, Erte Xiao
core  

A Master Wittgensteinian Surveys Human Nature -A Review of Human Nature-the Categorial Framework by PMS Hacker (2010) (review revised 2019) [PDF]

open access: yes, 2019
Materialism, reductionism, behaviorism, functionalism, dynamic systems theory and computationalism are popular views, but they were shown by Wittgenstein and more recently by Searle to be incoherent.
Starks, Michael
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Cognitive Function and Subjective Well-Being in Japanese Community-Dwelling Older Adults: A Cross-Sectional Study

open access: yesGeriatrics
Background: The relationship between mild cognitive impairment (MCI) and subjective well-being remains poorly understood. We examined associations between cognitive function and well-being domains in community-dwelling older Japanese adults with and ...
Baoxing Li   +4 more
doaj   +1 more source

Classification of Human Decision Behavior: Finding Modular Decision Rules with Genetic Algorithms [PDF]

open access: yes
The understanding of human behavior in sequential decision tasks is important for economics and socio-psychological sciences. In search tasks, for example when individuals search for the best price of a product, they are confronted in sequential steps ...
Daniel Schunk   +2 more
core  

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