Results 121 to 130 of about 5,199,515 (344)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Race-Based Social Rejection and Mental Health: The Role of Racial Identity

Trauma Care
Background and Introduction: Race-based social rejection has been found to predict post-traumatic stress and depression symptoms, consistent with previous studies that have shown the negative mental health effects of racism, as well as social rejection ...
Dorothy Chin, Tamra B. Loeb, Muyu Zhang, Michele Cooley-Strickland, Jennifer V. Pemberton, Gail E. Wyatt   +5 more
doaj   +1 more source

Supplementary Material for: 7-Methylxanthine Influences the Behavior of ADORA2A-DRD2 Heterodimers in Human Retinal Pigment Epithelial Cells

, 2022
Fan Yang, Li J, Liang Huang, Kan Wang, Mingwei Zhao   +4 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Project on Human Development in Chicago Neighborhoods (PHDCN): Child and Adolescent Behavior Rating Scale, Wave 2, 1997-2000

, 2014
Felton J. Earls, Jeanne Brooks‐Gunn, Stephen W. Raudenbush, Robert J. Sampson   +3 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Cognitive Function and Subjective Well-Being in Japanese Community-Dwelling Older Adults: A Cross-Sectional Study

Geriatrics
Background: The relationship between mild cognitive impairment (MCI) and subjective well-being remains poorly understood. We examined associations between cognitive function and well-being domains in community-dwelling older Japanese adults with and ...
Baoxing Li, Tianshu Chu, Ziming Gong, Le Tian, Hiro Kishimoto   +4 more
doaj   +1 more source

A Data-driven, Falsification-based Model of Human Driver Behavior [PDF]

, 2019
Nauman Sohani, Geunseob Oh, Xinpeng Wang
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Responses of Human-Habituated Wild Atlantic Spotted Dolphins to Play Behaviors Using a Two-Way Human/Dolphin Interface [PDF]

, 2012
Denise L. Herzing, Fabienne Delfour, Adam A. Pack   +2 more
openalex   +1 more source