Results 71 to 80 of about 5,187,370 (343)

Connectivity Differences between Human Operators of Swarms and Bandwidth Limitations [PDF]

open access: yes, 2012
Human interaction with robot swarms (HSI) is a young field with very few user studies that explore operator behavior. All these studies assume perfect communication between the operator and the swarm.
Chakraborty, Nilanjan   +5 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Assisted Versus Unassisted Domiciliary Alcohol Detoxification: A Randomized Controlled Trial

open access: yesIndian Journal of Psychological Medicine
Background: Detoxification stands as a crucial phase in the treatment of alcohol use disorders (AUD), yet only limited data is available on the outcomes of home-based detoxification. Assisted domiciliary detoxification involves monitoring an individual’s
Sneha B. Suresh, Anil V. Rane
doaj   +1 more source

Simulating the behavior of the human brain on GPUS [PDF]

open access: yes, 2018
The simulation of the behavior of the Human Brain is one of the most important challenges in computing today. The main problem consists of finding efficient ways to manipulate and compute the huge volume of data that this kind of simulations need, using ...
Labarta Mancho, Jesús José   +5 more
core   +4 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Reagent strips test: A simplified method for prompt analysis of cerebrospinal fluid in neurological disorders in emergency

open access: yesPractical Laboratory Medicine, 2019
Introduction: The initial examination of cerebrospinal fluid (CSF) for proteins, glucose, and leukocytes, is still the gold standard investigation in some neurological conditions like meningitis.
Anshu Gupta, Tanima Dwivedi
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Etiology, Assessment and Treatment of Compulsive Checking: A Review

open access: yesPsychology Research and Behavior Management
Sisi Guo, Mina Yadegar, Helen Khaw, Susanna Chang UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USACorrespondence: Sisi Guo, Email sisiguo@mednet.ucla.eduAbstract: Checking is the most reported compulsion of Obsessive ...
Guo S, Yadegar M, Khaw H, Chang S
doaj  

Shear viscosity and nonlinear behaviour of whole blood under large amplitude oscillatory shear [PDF]

open access: yes, 2013
We investigated experimentally the rheological behavior of whole human blood subjected to large amplitude oscillatory shear under strain control to assess its nonlinear viscoelastic response.
Alves, M.A.   +6 more
core   +1 more source

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