Results 81 to 90 of about 12,614,860 (303)

Detection of Unusual Human Activities Based on Behavior Modeling [PDF]

open access: yes, 2014
A type of services that require human physical actions and intelligent decision making exists in various real fields, such as nursing in hospitals and caregiving in nursing homes.
Hiraishi, Kunihiko, Kobayashi, Koichi
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Assisted Versus Unassisted Domiciliary Alcohol Detoxification: A Randomized Controlled Trial

open access: yesIndian Journal of Psychological Medicine
Background: Detoxification stands as a crucial phase in the treatment of alcohol use disorders (AUD), yet only limited data is available on the outcomes of home-based detoxification. Assisted domiciliary detoxification involves monitoring an individual’s
Sneha B. Suresh, Anil V. Rane
doaj   +1 more source

From E-learning to generative AI: Perspectives on technology acceptance and human behavior in education [PDF]

open access: yes
This study systematically maps the intellectual structure and thematic evolution of technology acceptance research in education, with a specific focus on how human behavior is represented in technology-mediated learning contexts. Using BERTopic, a neural
Yalçın, Yasin   +4 more
core   +1 more source

The ‘Human Rights Component’ of Foreign Policy

open access: yes, 2022
Framed into the broader conceptual debate that addresses the controversial role of human rights in the foreign policies of states, this book aims to critically investigate whether, how and to what extent human rights matter in the definition of Italy’s ...
de Perini, Pietro
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Multitasking and coordinating framework for human\ud information behavior

open access: yes, 2006
New Directions in Human Information Behavior, co-edited by Drs. Amanda Spink and Charles Cole provides an understanding of the new directions, leading edge theories and models in human information behavior.
Spink, Amanda H.   +2 more
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Reagent strips test: A simplified method for prompt analysis of cerebrospinal fluid in neurological disorders in emergency

open access: yesPractical Laboratory Medicine, 2019
Introduction: The initial examination of cerebrospinal fluid (CSF) for proteins, glucose, and leukocytes, is still the gold standard investigation in some neurological conditions like meningitis.
Anshu Gupta, Tanima Dwivedi
doaj   +1 more source

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