Results 71 to 80 of about 12,614,860 (303)

Providing effective feedback, monitoring and evaluation to on-line collaborative learning discussions

open access: yes, 2011
Learning and knowledge building have become critical competences for people in the knowledge society era. In this paper, we propose a sociolinguistic dialogue model for understanding how learning evolves and how cognitive process is constructed in on ...
Daradoumis Haralabus, Atanasi   +3 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Etiology, Assessment and Treatment of Compulsive Checking: A Review

open access: yesPsychology Research and Behavior Management
Sisi Guo, Mina Yadegar, Helen Khaw, Susanna Chang UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USACorrespondence: Sisi Guo, Email sisiguo@mednet.ucla.eduAbstract: Checking is the most reported compulsion of Obsessive ...
Guo S, Yadegar M, Khaw H, Chang S
doaj  

Opinion of Ecuadorians on Migration in the Target Country: Benefits and Challenges

open access: yesSocial Sciences
Migration plays a crucial role in shaping destination countries’ social and economic landscapes, including in Ecuador. This study aims to explore the benefits and challenges of migration by analyzing the perceptions of Ecuadorians who have directly or ...
Angel Torres-Toukoumidis   +2 more
doaj   +1 more source

Creative Applications of Human Behavior Understanding

open access: yes, 2013
LIDIA
Oya Aran   +7 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Ventrolateral prefrontal-amygdala repetitive transcranial magnetic stimulation (rTMS) modulation of impulsivity in borderline personality disorder: a proof-of-concept study

open access: yesScientific Reports
Impulsivity and emotional dysregulation are core symptoms of Borderline Personality Disorder (BPD) for which therapeutic options are very limited. Prior neuroimaging studies suggest that BPD symptoms may be related to fronto-amygdala circuit dysfunction.
Reza Tadayonnejad   +7 more
doaj   +1 more source

Towards a theory of human behavior : emphasis family centricity

open access: yes, 1976
The purpose of the study was to advance the understanding of human behavior. In order to do so, a theory emphasizing the importance of family interactions with regard to both their effects on individuals and their centricity in understanding social ...
Miracle, Wayne, 1940-
core  

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