Results 81 to 90 of about 5,187,370 (343)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Future Neurology, 2007 The development of the frontal systems is a major evolutionary advancement of the human race. It enables the regulation of behaviors in accordance with goals and, hence, frees humans from the constraints imposed by our basic physiological instincts. The burgeoning neuroscience and neuropsychology literature has consistently highlighted the important ...
Lee, TMC, Leung, AWS, Chan, CCH
openaire +3 more sources
Online backchannel synthesis evaluation with the switching Wizard of Oz [PDF]
, 2012 In this paper, we evaluate a backchannel synthesis algorithm in an online conversation between a human speaker and a virtual listener. We adopt the Switching Wizard of Oz (SWOZ) approach to assess behavior synthesis algorithms online.
Heylen, Dirk +2 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Monkeys increase scratching when encountering unexpected good fortune
Scientific ReportsElucidating how ancestral behavioural traits have been repurposed for psychological and social functions is critical to advancing our understanding of human behavioural evolution.
Sakumi Iki, Ikuma Adachi
doaj +1 more source
Case Reports in Pathology, 2012 An 11-year-old girl presented with progressively increasing swelling in scalp of 8-month duration with no neurological deficit. Local examination showed a hard swelling that seemed to be arising from frontal bone.
Anshu Gupta +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Robust Bayesian analysis of animal networks subject to biases in sampling intensity and censoring
Methods in Ecology and EvolutionData collection biases are a persistent issue for studies of social networks. This issue has been particularly important in animal social network analysis (ASNA), where data are often unevenly sampled and such biases may potentially lead to incorrect ...
Sebastian Sosa +3 more
doaj +1 more source
AlignDiff: Aligning Diverse Human Preferences via Behavior-Customisable Diffusion Model [PDF]
, 2023 Zibin Dong +9 more
openalex +1 more source