Results 221 to 230 of about 7,502,790 (265)

Reduction of Testicular Human Chorionic Gonadotropin Receptors by Human Chorionic Gonadotropin in vivo and in vitro

Hormone Research, 2008
Changes in rat and human testicular human chorionic gonadotropin (hCG) binding sites induced by hCG were estimated in vivo and in vitro. After a single administration of hCG, the specific 125I-hCG bindings were significantly reduced for 7 and 5 days in rat and human testes, respectively.
M, Namiki, M, Kitamura, N, Nonomura, M, Nakamura, A, Okuyama, M, Utsunomiya, H, Itatani, T, Sonoda, K, Matsumoto   +8 more
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Human chorionic gonadotropin in commercial human menopausal gonadotropin preparations

Fertility and Sterility, 1993
Several studies indicated the presence of an hCG-immunoreactive substance in commercial hMG preparations. Because hCG represents LH activity with a relatively very long half-life, differences between hMG preparations with respect to hCG content could imply clinical differences.
P G, Stokman, R, de Leeuw, H A, van den Wijngaard, H J, Kloosterboer, H M, Vemer, A L, Sanders   +5 more
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Human chorionic gonadotropin and malignant mesothelioma

Cancer, 1979
A 56-year-old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had ...
S, Rich, C A, Presant, J, Meyer, S C, Stevens, D, Carr   +4 more
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Thyrotropic Action of Human Chorionic Gonadotropin

Thyroid, 1995
Hyperthyroidism or increased thyroid function has been reported in many patients with trophoblastic tumors. In these cases, greatly increased human chorionic gonadotropin (hCG) levels and suppressed TSH levels suggest that hCG has thyrotropic activity.
M, Yoshimura, J M, Hershman
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Carboxypeptidase Digestion of Human Chorionic Gonadotropin

Endocrine Research Communications, 1977
Native human chorionic gonadotropin (hCG) was resistant to carboxypeptidase digestion even in the presence of urea. Isolated alpha subunit of the hormone (hCG-alpha), though unreactive to enzyme treatment in the absence of denaturant, released up to four amino acid residues from the C-terminus on incubation with a mixture of carboxypeptidases A and B ...
V G, Hum, H G, Botting, K F, Mori
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Immunologic Reactions to Human Chorionic Gonadotropin

The Journal of Clinical Endocrinology & Metabolism, 1962
ABSTRACT. A preparation of human chorionic gonadotropin (HCG) was injected with Freund's adjuvant into rabbits, resulting in the production of an antiserum that had precipitating properties. By using the rat ventral prostate method of bio-assay, it was possible to demonstrate the antihormonal properties of the antiserum.
D K, KEELE, J, REMPLE, J, BEAN, J, WEBSTER   +3 more
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The reaction of tetranitromethane with human chorionic gonadotropin

Archives of Biochemistry and Biophysics, 1976
Abstract The reaction of tetranitromethane with human chorionic gonadotropin and its subunits has been investigated. The hormone consists of two subunits, α and β, containing four and three tyrosyl residues, respectively. Introduction of 1 nitrated tyrosine residue into the native hormone was accompanied by a 20% loss in immunological reactivity and ...
R B, Carlsen, O P, Bahl
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Crystal structure of human chorionic gonadotropin

Nature, 1994
The three-dimensional structure of human chorionic gonadotropin shows that each of its two different subunits has a similar topology, with three disulphide bonds forming a cystine knot. This same folding motif is found in some protein growth factors. The heterodimer is stabilized by a segment of the beta-subunit which wraps around the alpha-subunit and
A J, Lapthorn, D C, Harris, A, Littlejohn, J W, Lustbader, R E, Canfield, K J, Machin, F J, Morgan, N W, Isaacs   +7 more
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THE CYTOLOGICAL LOCALIZATION OF HUMAN CHORIONIC GONADOTROPIN

Canadian Journal of Biochemistry and Physiology, 1963
The indirect fluorescent antibody technique was used to determine the cellular site of human chorionic gonadotropin (H.C.G.) in normal and toxaemic placentas, and in choriocarcinomas. In placental tissue specific fluorescence was located in the syncytial cells of the chorionic villi but not in the cytotrophoblast cells.
A, LEZNOFF, B A, DAVIS
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Tissue distribution of human chorionic gonadotropin

American Journal of Obstetrics and Gynecology, 1970
Abstract Tissue distribution of exogenous HCG was studied in adult female mice injecting the animals with HCG-I 125 , BSA-I 125 , and I 125 and determining in a scintillation counter the tissue radioactivity at various time intervals. The radioactive materials were extracted from the tissues and mixed with excess anti-HCG serum. It was found that the
S, Kazeto, M M, Hreshchyshyn
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