Results 221 to 230 of about 9,004,562 (264)
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Crystal structure of human chorionic gonadotropin
Nature, 1994The three-dimensional structure of human chorionic gonadotropin shows that each of its two different subunits has a similar topology, with three disulphide bonds forming a cystine knot. This same folding motif is found in some protein growth factors. The heterodimer is stabilized by a segment of the beta-subunit which wraps around the alpha-subunit and
A J, Lapthorn +7 more
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Human chorionic gonadotropin and the fetal allograft
American Journal of Obstetrics and Gynecology, 1972Abstract With the use of the mixed-lymphocyte-culture reaction, it is shown that human chorionic gonadotropins (HCG) can inhibit this reaction only at concentrations above those normally present throughout most of pregnancy and of the order of that found in maternal serum at the time of the HCG peak at the end of the first trimester. The significance
D M, Jenkins +3 more
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Human chorionic gonadotropin and malignant mesothelioma
Cancer, 1979A 56-year-old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had ...
S, Rich +4 more
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Thyrotropic Action of Human Chorionic Gonadotropin
Thyroid, 1995Hyperthyroidism or increased thyroid function has been reported in many patients with trophoblastic tumors. In these cases, greatly increased human chorionic gonadotropin (hCG) levels and suppressed TSH levels suggest that hCG has thyrotropic activity.
M, Yoshimura, J M, Hershman
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Carboxypeptidase Digestion of Human Chorionic Gonadotropin
Endocrine Research Communications, 1977Native human chorionic gonadotropin (hCG) was resistant to carboxypeptidase digestion even in the presence of urea. Isolated alpha subunit of the hormone (hCG-alpha), though unreactive to enzyme treatment in the absence of denaturant, released up to four amino acid residues from the C-terminus on incubation with a mixture of carboxypeptidases A and B ...
V G, Hum, H G, Botting, K F, Mori
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Nature of the Subunits of Human Chorionic Gonadotropin
Endocrinology, 1971Subunits of human chorionic gonadotropin have been isolated from carboxymethyl- HCG by preparative poly aery lamide electrophoresis, by chromatography on Sephadex G-25, and from native HCG by chromatography on DEAE-Sephadex A-25. HCG-α subunit has been estimated to have a Stokes’ radius of 23.3 A by gel filtration and a molecular weight by SDSgel ...
F J, Morgan, R E, Canfield
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Immunology of Human Chorionic Gonadotropin (HCG)
1967Publisher Summary This chapter discusses the immunology of human chrionic gonadotropin (HCG). It also reviews the immunology of HCG, examples of various disciplines involved in hormone research where immunological methods are employed. These include the characterization of HCG preparations, the detection of contaminating proteins, quantitative ...
B, Lunenfeld, A, Eshkol
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Human chorionic gonadotropin hormone is antiviral
Medical Hypotheses, 1996Although it is well known that human chorionic gonadotropin maintains the corpus luteum's ability to secrete estrogen and progesterone, I believe that it serves yet another important function. Early evidence suggests that human chorionic gonadotropin is a broad-spectrum antiviral/immune potentiator.
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