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Variants of Human Cytomegalovirus

1982
Antigenic variations of human cytomegaloviruses were first detected by cross-neutralization tests. Weller et al. (1960) reacted sera from two babies (named Davis and Esp.) with isolates from themselves, with isolates from each other, and with AD169, an isolate from adenoids (Rowe et al., 1956).
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Consequences of human cytomegalovirus mimicry

Human Immunology, 2004
The HCMV genome has evolved with its host by incorporating a series of genes that are homologous to, or functionally mimic, cellular genes. Some are designed to counteract the stress of infection on the host cell, notably the viral antiapoptotic proteins (vICA, vMIA). Others potentially help the infected cell maintain a low immunologic profile.
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Human Cytomegalovirus and the Neutrophil

2018
Medical Research Council Research Clinical Fellowship Addenbrooke's Charitable ...
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Human cytomegalovirus vaccines

2007
Efforts to develop a human cytomegalovirus (HCMV) vaccine began more than 30 years ago in response to then recent reports that HCMV was capable of causing severe congenital disease. During the intervening years, our understanding of HCMV biology and immunology has increased dramatically.
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Human cytomegalovirus and immunopathology

Springer Seminars in Immunopathology, 2002
Mark R. Wills   +4 more
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Control of Apoptosis by Human Cytomegalovirus

2008
Caspase-dependent apoptosis has an important role in controlling viruses, and as a result, viruses often encode proteins that target this pathway. Caspase-dependent apoptosis can be activated from within the infected cell as an intrinsic response to replication-associated stresses or through death-inducing signals produced extrinsically by immune cells.
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Human Cytomegalovirus Infection in Transplantation

Nephron, 1993
Claudia A. Müller   +3 more
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