Results 61 to 70 of about 204,642 (262)

Towards a Prophylactic Vaccine for the Prevention of HCMV Infection

Vaccines, 2021
Human cytomegalovirus (HCMV) or human herpesvirus 5, is a ubiquitous human herpesvirus, which can cause severe disease in immunocompromised patients (AIDS patients and solid organ transplant or hematopoietic stem cell transplant recipients) [...]
Gaëtan Ligat, Sophie Alain, Sébastien Hantz   +2 more
doaj   +1 more source

Alveolar Macrophages Isolated Directly From Human Cytomegalovirus (HCMV)-Seropositive Individuals Are Sites of HCMV Reactivation In Vivo. [PDF]

, 2015
Human cytomegalovirus (HCMV) causes significant morbidity in the immunocompromised host. Following primary infection, the virus establishes latent infection in progenitor cells of the myeloid lineage.

core   +1 more source

Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size [PDF]

, 2016
Cytomegalovirus (CMV) infection is one of the most common persistent viral infections in humans worldwide and is epidemiologically associated with many adverse health consequences during aging.
A Harari, A Lelic, AM Simanek, AR Hersperger, AW Sylwester, C Courivaud, C Riou, E Derhovanessian, E Gimenez, E Sinclair, EJ Wherry, ET Roberts, F Bihl, F Kern, F Sallusto, G Makedonas, G Makedonas, G Pawelec, G Pawelec, GC Wang, GC Wang, IG Rodrigue-Gervais, J Cheng, J van Zanten, JM Fletcher, L Cicin-Sain, L Cicin-Sain, L Krol, ML Pita-Lopez, MR Betts, MR Wills, N Khan, P Trzonkowski, PA Darrah, Q Ouyang, R Lachmann, R Solana, R Vescovini, RA Seder, RA van Lier, S Cantisan, SA Migueles, SH Park, SR Hadrup, T Crough, V Appay, YL Chiu, YN Ji   +47 more
core   +1 more source

Artifact‐Minimizing Ultrathin Transparent Electrodes Fabricated via iCVD for In Vivo Optogenetic Stimulation and Neural Signal Monitoring of Primary Visual Cortex

Advanced Functional Materials, EarlyView.
We present ultrathin flexible transparent electrodes through iCVD‐enabled molecular control of 10 nm gold films on poly(dimethylaminomethylstyrene). In vivo validation demonstrated photoelectric artifact reduction vs. opaque electrodes and preservation of natural neural dynamics.
Tae Jin Mun, Minju Kim, Chaesung Kim, Yunyoung Choi, In‐Yeop Baek, Younghak Cho, Gyeongyong Lee, Yerim Jang, Min‐Ho Nam, Wonryung Lee, Maesoon Im, Hyejeong Seong   +11 more
wiley   +1 more source

Pre-Transplant Platelet Refractoriness and Alternative Donors Are Associated With Cytomegalovirus Retinitis in Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundCytomegalovirus retinitis is a severe, vision-threatening opportunistic infection in an immunodeficient population. Reports on cytomegalovirus retinitis in hematopoietic stem cell transplant recipients due to severe aplastic anemia have been ...
Yuehong Zhang, Yuqin Liang, Xu Zhang, Shunqing Wang, Jinpeng Cao, Jinpeng Cao, Zongyin Gao, Ling Li, Wenjian Mo   +8 more
doaj   +1 more source

The Core Histone-binding Region of the Murine Cytomegalovirus 89K Immediate Early Protein [PDF]

, 1991
The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA-associated and isolated histones in vitro. We characterized the histone-binding region of pp89 and its cellular localization during cell division to ...
Bühler, Bernhard, Koszinowski, Ulrich H., Messerle, Martin, Münch, Konrad   +3 more
core   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Cytomegalovirus (CMV) Infection and Latency

Pathogens, 2021
Cytomegalovirus (CMV) is a herpesvirus that infects a majority of the human population worldwide [...]
Christine M. O’Connor
doaj   +1 more source

Evolution of the G+C content frontier in the rat cytomegalovirus genome [PDF]

, 2008
Within the 230138 bp of the rat cytomegalovirus (RCMV) genome, the G+C content changes abruptly at position 142644, constituting a G+C content frontier. To the left of this point, overall G+C content is 69.2%, and to the right it is only 47.6%.
Gatherer, Derek
core   +3 more sources

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source