Results 121 to 130 of about 12,782,052 (246)

A Novel CD24+ Subpopulation For Pulpitis Traeatment And Pulp Regeneration

International Dental Journal
Aim or purpose: The pulp regeneration strategy is important to treat pulpitis and pulp necrosis. Yet the key functional subpopulation and mechanism that governs the odontogenic fate decisions remain largely unknown. Materials and methods: In our study, a
Cheng Liang
doaj   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Human dental pulp stem/stromal cells in clinical practice

World Journal of Stem Cells
Dental pulp stem/stromal cells (DPSCs) are fibroblast-like, neural crest-derived, and multipotent cells that can differentiate into several lineages. They are relatively easy to isolate from healthy and inflamed pulps, with little ethical concerns and can be successfully cryopreserved and thawed.
openaire   +2 more sources

Proteomic Analysis of Stromal Cells Derived from the Dental Pulp of Human Exfoliated Deciduous Teeth

, 2010
Human dental pulp derived from exfoliated deciduous teeth has been described as a promising alternative source of multipotent stem cells. While these cells share certain similarities with mesenchymal stem-like cells (MSC) isolated from other tissues ...
Venalis, Algirdas,, Savickiene, Jurate,, Tunaitis, Virginijus,, Navakauskiene, Ruta,, Treigyte, Grazina,, Aldonyte, Ruta,, Magnusson, Karl-Eric,, Suriakaite, Kristina,, Jarmalaviciute, Akvile,, Navakauskas, Dalius,, Surovas, Andrejus,, Borutinskaite, Veronika,, Liutkevicius, Evaldas,, Matuzevicius, Dalius,, Pivoriunas, Augustas,   +14 more
core   +1 more source

R‐Loops Mediated Odontogenic Differentiation of hDPSCs by Activating the cGAS‐STING Pathway Under Inflammatory Microenvironment

Oral Diseases, EarlyView.
ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang, Yiqing Wang, Yating Miao, Zhipu Luo, Lin Niu, Ruirui Liu   +5 more
wiley   +1 more source

Biobanking of human teeth for stem cell storage: preserving stem cells for future needs

Journal of the Pakistan Medical Association
Human teeth serve as a potential reservoir for post-embryonic mesenchymal dental stem cells. Researchers have identified and isolated seven types of dental stem cells from pulp and periodontal ligament tissues.
Saqib Habib, Shahrukh Ali Khan, Aqeel Ahmed, Farhan Raza Khan   +3 more
doaj   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Isolation and Differentiation of Dental Pulp Stem Cells into Odontoblastic Lineage

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2014
BACKGROUND AND OBJECTIVE: Limited resources for adult stem cells necessitate appropriate methods for isolation, proliferation and differentiation of these cells.
Maryam Raoof, ali Mohammadi Kamal-abadi, Mohammad Mehdi Yaghoobi, razieh kooshki, Mehdi Abbasnejad, ali Derakhshani   +5 more
doaj  

CGRP-mediated neuro-vascular-pulp cell crosstalk is essential for dental pulp repair

Frontiers in Cell and Developmental Biology
IntroductionThe repair of dental pulp injury is the cornerstone of vital pulp therapy. Traditional research has predominantly focused on the roles of immune cells, vascular endothelial cells, and dental pulp stem cells, often overlooking the active ...
Zixin Wu, Junyang Chen, Yiming Zhao, Zhenjuan Zhou, Rui Lin, Wei Liu, Wei Liu   +6 more
doaj   +1 more source

Dose‐dependent effects of photobiomodulation on stem cells from human exfoliated deciduous teeth cultured on polylactic acid films: An in vitro study

Photochemistry and Photobiology, EarlyView.
660‐nm photobiomodulation increased metabolic activity, modulated cell cycle distribution, and increased apparent surface coverage in dental stem cells cultured on polylactic acid films, with 4 J/cm2 producing the most consistent response and a greater G2/M fraction than 1 J/cm2.
Rômulo Augusto de Paiva Macedo, Vladimir Galdino Sabino, Hugo Alexandre Oliveira Rocha, Moacir Franco de Oliveira, Carlos Eduardo Bezerra de Moura, Carlos Augusto Galvão Barboza   +5 more
wiley   +1 more source