Results 161 to 170 of about 60,877 (261)

Starfish-Derived Extracts Enhance Mitophagy and Suppress Senescence-Associated Markers in Human Dermal Fibroblasts. [PDF]

Mar Drugs
Lee HJ, Kim J, Won B, Lee DH, Shin OS.
europepmc   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

The First Simplified Heparan Sulphate-Alginate Hybrid Trisaccharides: Synthesis and Biological Effects on Human Dermal Fibroblasts. [PDF]

Int J Mol Sci
Kútvölgyi K, Peleskei Z, Demeter F, Barta RA, Mándi A, Homoki E, Oláh A, Hajkó J, Herczeg M, Lisztes E.   +9 more
europepmc   +1 more source

Heat Stress Promotes Fibroblast‐Derived WNT5A Secretion Through m6A Modification to Activate Melanogenesis

Advanced Science, EarlyView.
Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan, Yaqing Wen, Yushan Zhang, Lan Zhang, Jianjian Zhu, Zhen Tang, Ling Jiang, Chuhan Fu, Shu Zhou, Keyi Zhang, Jiangfeng Huang, Li Lei, Jing Chen, Qinghai Zeng   +13 more
wiley   +1 more source

Lipopolysaccharide-Activated Macrophages Suppress Cellular Senescence and Promote Rejuvenation in Human Dermal Fibroblasts. [PDF]

Int J Mol Sci
Inagawa H, Kohchi C, Uehiro M, Soma GI.
europepmc   +1 more source

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

Advanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang, Jiaxin Tian, Xiaolong Zhu, Xiao Li, Xiangshu Qiu, Yuanyuan Li, Ben Zhong Tang, Ning Shi   +7 more
wiley   +1 more source

The Effect of Blue Light on Mitochondria in Human Dermal Fibroblasts and the Potential Aging Implications. [PDF]

FASEB J
McNish H, Mathapathi MS, Figlak K, Damodaran A, Birch-Machin MA.   +4 more
europepmc   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Enhanced in vitro wound healing of human dermal fibroblasts using nanohydroxyapatite synthesized from Elaeagnus Angustifolia and loaded with crocin. [PDF]

BMC Complement Med Ther
Azaryan E, Ghodousi A, Hanafi-Bojd MY, Naseri M.   +3 more
europepmc   +1 more source