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Antiphotoaging effect of chitooligosaccharides on human dermal fibroblasts
Photodermatology, Photoimmunology & Photomedicine, 2012SummaryBackground/PurposeIn the present study, the effect of 3–5 kDa chitooligosaccharide (COS) on homeostasis between the expression of collagen‐degrading matrix metalloproteinases (MMPs) and collagen synthesis was investigated using ultraviolet (UV)‐A irradiated dermal fibroblasts.MethodsUV protection imparted by 3–5 kDa COS was measured by examining
Jung-Ae, Kim +5 more
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Characterization of Human Dermal Fibroblasts in Fabry Disease
Journal of Cellular Physiology, 2015Fabry disease (FD) is a hereditary X‐linked metabolic lysosomal storage disorder due to insufficient amounts or a complete lack of the lysosomal enzyme α‐galactosidase A (α‐GalA). The loss of α‐GalA activity leads to an abnormal accumulation of globotriaosylcerami (Gb3) in lysosomes and other cellular components of different tissues and cell types ...
LAKOMA, JARMILA +3 more
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Isolation and Culture of Human Dermal Fibroblasts
2019Dermal fibroblasts are the main cell type present in skin connective tissue (dermis). Fibroblasts interact with epidermal cells during hair development and in interfollicular skin. Moreover, they play an essential role during cutaneous wound healing and in bioengineering of skin. Hence, culture of primary fibroblast is gaining in importance.
Kisiel MA, Klar AS
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Effects of Tamoxifen on Normal Human Dermal Fibroblasts
Archives of Facial Plastic Surgery, 2006Objective: To evaluate the effects of tamoxifen on the growth and autocrine growth factor production of human dermal fibroblasts from the face. Methods: In vitro study of normal adult dermal fibroblast cells developed from surgical ...
Mauro B, Ruffy +2 more
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Adhesion and Proliferation of Human Dermal Fibroblasts on Collagen Matrix
Journal of Biomaterials Applications, 2004The purpose of this study was to evaluate adhesion and growth of human dermal fibroblasts on a 0.150 mm-thick matrix of reconstituted collagen isolated from horse tendon. Collagen was extracted and polymerized according to the standard procedures (Opocrin, Corlo, Modena, Italy).
CROCE, Maria Antonietta +6 more
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NATURAL KILLER CELLS ACTIVATE HUMAN DERMAL FIBROBLASTS
Cytokine, 2000Human dermal fibroblasts (HDF) undergo activation and secrete cytokines when cocultured with T cells. Here, we identify potent activators of HDF among human peripheral CD2(+)-lymphocytes. Populations with strong HDF activating capacity consisted essentially of cells with a natural killer (NK) surface marker phenotype (CD3(-), CD4(-), CD8(-), CD56 ...
Müller KM +3 more
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Biological effects of cellular stretch on human dermal fibroblasts
Journal of Plastic, Reconstructive & Aesthetic Surgery, 2013Pathological scars are fibroproliferative skin disorders that are characterised by the accumulation of fibroblasts and collagens. It is increasingly understood that their development and progression may be related to local skin mechanics, such as stretching.
Chenyu, Huang +5 more
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Isolation and Culture of Human Dermal Fibroblasts
Dermal fibroblasts are the main cell type present in skin connective tissue (dermis). They are responsible for the synthesis of dermal extracellular matrix (ECM), providing mechanical stability for the dermal layer. In addition, fibroblasts interact with epidermal cells during hair development and in interfollicular skin cells through bidirectional ...Ziliani, Fabiana +2 more
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UVB irradiation on human dermal fibroblasts
2023UVB is a primary contributor to extrinsic skin aging, and a comprehensive understanding of its impact on human skin is crucial for elucidating the aging process and facilitating the development of effective drug treatments. Additionally, UVB plays a pivotal role in vitamin D synthesis within dermal fibroblasts, underscoring its positive effects on ...
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IL-4 Induces Eotaxin in Human Dermal Fibroblasts
International Archives of Allergy and Immunology, 1999A common feature of Th2-mediated skin diseases is selective eosinophil (Eo) infiltration in the affected dermis. However, the mechanisms of selective Eo recruitment are not yet fully understood. Our recent findings indicated that dermal fibroblasts actively participate in the accumulation of Eo in Th2-mediated skin inflammation.
M, Mochizuki +3 more
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