Results 121 to 130 of about 34,966,316 (347)

Bridging the Gap: Orchestrating Indonesian Higher Education

open access: yesJurnal Manajemen Teori dan Terapan
Objective: This study aims to ascertain the extent of the gap between the human resources presently available in the Republic of Indonesia (the number of study programs classified into fields of science existing in Indonesian higher education) and those ...
Agus Harimurti Yudhoyono   +3 more
doaj   +1 more source

Aid, Conflict and Human Development [PDF]

open access: yes
A large and growing literature addresses the impact of foreign aid on the growth of per capita incomes in recipient countries. While this link is important, given its implications for poverty reduction, an arguably more important link is that between aid
Farhad Noorbakhsh, Mark McGillivray
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

A Perceived Human Development Index [PDF]

open access: yes
The objective of the paper is to build a Perceived Human Development Index (PHDI) framework by assembling the HDI components, namely indicators on income, health and education on their subjective version.
Neri, Marcelo Cortes
core  

The future of space exploration and human development [PDF]

open access: yes, 2008
This repository item contains a single issue of The Pardee Papers, a series papers that began publishing in 2008 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future.
Kalam, A.P.J. Abdul
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Economic Growth and Human Development - [PDF]

open access: yes
This paper explores the links between economic growth and human development, identifying two chains, one from economic growth to human development, and the other, conversely, from human development to economic growth.
Alejandro Ramirez   +2 more
core  

A model for the control mode man-computer interface dialogue [PDF]

open access: yes, 1981
A four stage model is presented for the control mode man-computer interface dialogue. It consists of context development, semantic development syntactic development, and command execution.
Chafin, R. L.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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