Predicting tumour resistance to paclitaxel and carboplatin utilising genome-wide screening in haploid human embryonic stem cells. [PDF]
Nissenbaum J +10 more
europepmc +1 more source
Through HPLC–MS/MS analysis and multivariate statistics, raphani semen (RS) varieties with high functional components were screened. The white raphani semen “Xuebawang” was identified as ideal for further study due to its high bioactive content: glucoraphenin (9010.27 mg/100 g), glucoraphanin (1027.76 mg/100 g), sulforaphane (66.14 mg/100 g), and ...
Yonghua Li +10 more
wiley +1 more source
O-GlcNAcase regulates pluripotency states of human embryonic stem cells. [PDF]
Liu Q +8 more
europepmc +1 more source
Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser +6 more
wiley +1 more source
Enhancing terminal erythroid differentiation in human embryonic stem cells through TRIB3 overexpression. [PDF]
Wang X +12 more
europepmc +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Cumulus cells conditioned medium facilitates germ cell differentiation from human embryonic stem cells: An experimental study. [PDF]
Tahajjodi SS +7 more
europepmc +1 more source
Uncertainty‐Guided Selective Adaptation Enables Cross‐Platform Predictive Fluorescence Microscopy
Deep learning models often fail when transferred to new microscopes. A novel framework overcomes this by selectively adapting the early layers governing low‐level image statistics, while freezing deep layers that encode morphology. This uncertainty‐guided approach enables robust, label‐free virtual staining across diverse systems, democratizing ...
Kai‐Wen K. Yang +9 more
wiley +1 more source
Selective Elimination of Genetic Variants of Human Embryonic Stem Cells from High Vulnerability to Ferroptosis. [PDF]
Kim YJ +6 more
europepmc +1 more source
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo +3 more
wiley +1 more source

