Results 131 to 140 of about 31,425 (209)

Genetic Characterization and Multidisciplinary Management of Complete Androgen Insensitivity Syndrome: Unveiling a Novel AR Mutation

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A novel AR frameshift mutation (c.2023_2035del) was identified in a 17‐year‐old phenotypic female with Complete Androgen Insensitivity Syndrome (CAIS). This report emphasizes the necessity of molecular characterization and multidisciplinary management to address diagnosis, surgical timing, and psychological well‐being in disorder of sex ...
Astorino Maria Francesca, Scalise Serena, Di Bella Chiara, La Rosa Maria Angela, Piraino Basilia, Calabrò Marco, Gentile Mattia, Ruggeri Rosaria Maddalena, Esposito Emanuela, Briuglia Silvana, Cannavò Salvatore   +10 more
wiley   +1 more source

Three-Dimensional Structure of Human Epididymis Protein 4 (HE4): A Protein Modelling of an Ovarian Cancer Biomarker Through In Silico Approach

Journal of Tropical Life Science
The Human Epididymis Protein 4 (HE4) biomarker has been extensively investigated for its potential in diagnosing ovarian cancer (OC). For the application of diagnostic techniques and drug delivery, it is crucial to understand the protein tertiary ...
Nur Nadiah Abdul Rashid, Mohd Hamzah Mohd Nasir, Nurasyikin Hamzah, Che Muhammad Khairul Hisyam Ismail, Siti Aishah Sufira Nor Hishamuddin, Izzat Fahimuddin Mohamed Suffian, Azzmer Azzar Abdul Hamid   +6 more
doaj   +1 more source

A Case of Testicular Malakoplakia With Markedly High Signal Intensity on Fat‐Suppressed T1‐Weighted Images

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Testicular malakoplakia is a very rare, chronic granulomatous inflammatory condition that frequently resembles testicular malignancy on imaging studies. Here, we report a case of testicular malakoplakia with characteristic magnetic resonance imaging (MRI) findings and present a brief review of the literature.
Fumiko Yagi, Hirotaka Akita, Takeo Kosaka, Akihisa Ueno, Teppei Kotera, Masato Kobayashi, Hideaki Mekada, Mototsugu Oya, Masahiro Jinzaki   +8 more
wiley   +1 more source

Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Yahya Kanani, Ahmad Oryan, Abdollah Derakhshandeh   +2 more
wiley   +1 more source

Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik, Shreya Joshi, Aisha Nazli, Charu Kaushic   +3 more
wiley   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, Volume 14, Issue 4, Page 1017-1028, May 2026.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Use of Sensor Array Analysis to Detect Ovarian Cancer through Breath, Urine, and Blood: A Case-Control Study

Diagnostics
Ovarian cancer (OC) is the eighth most common cancer in women. Since screening programs do not exist, it is often diagnosed in advanced stages. Today, the detection of OC is based on clinical examination, transvaginal ultrasound (US), and serum biomarker
Roberto Angioli, Marco Santonico, Giorgio Pennazza, Roberto Montera, Daniela Luvero, Alessandra Gatti, Alessandro Zompanti, Panaiotis Finamore, Raffaele Antonelli Incalzi   +8 more
doaj   +1 more source

Human Epididymis Protein 4: A Prognostic Tool for Epithelial Ovarian Cancer [PDF]

Background: Human epididymis protein 4 (HE4) also referred to as whey acidic protein (WAP) is a promising and heavily studied biomarker for ovarian cancer.
Luansing, Jean
core   +1 more source

Cadmium Effects of Metallothionein Expression in Epididymal Epithelium of Rat [PDF]

, 2007
Cadmium (Cd) is a heavy metal with public health importance because it is known to present environmental and occupational hazards and a threatening to public health. Cd has negative effects on the liver, kidney, and male fertility.
Tang, Zilue
core  

Paternal sleep deprivation and cardiac dysfunction in offspring: A perspective of myocardial hypertrophy

Experimental Physiology, Volume 111, Issue 5, Page 2518-2527, 1 May 2026.
Abstract The objective of this work is to assess the effects and potential process of paternal acute sleep deprivation on cardiac function in their offspring. Male and female C57BL/6N mice aged 8–9 weeks (n = 4–5 mice/group) were used. Male mice were selected to construct an acute sleep deprivation model using the modified multiple platform method ...
Yingying Zhang, Leyao Wang, Jie Wang, Yun Pan, Wen Sun, Zhiwei Zou, Wenlin Bai, Ruiling Fang, Yue Zhang, Ping Zhang, Yuanbao Zhang, Lijian Lei, Wenping Zhang   +12 more
wiley   +1 more source