Results 91 to 100 of about 8,775,558 (296)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Lethal Experimentation on Human Beings: Roe\u27s Effect on Bioethics [PDF]
, 2004 Beginning with the assumption that human life begins at conception, this article explores the problematic terrain accompanying embryonic stem cell research and human cloning.
Saunders, Jr., William L.
core +1 more source
O Mundo da Saúde, 2014 The present article is the result of a bibliographical survey that seeks to present, by using a methodology based on the hypothetical-deductive method, to present a reflection on the biotechnological advances taking in consideration the vulnerability of ...
Angelita Maria Maders
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Future Internet, 2017 As Augmented Reality (AR) applications become commonplace, the determination of a device operator’s subjective Quality of Experience (QoE) in addition to objective Quality of Service (QoS) metrics gains importance. Human subject experimentation is common
Brian Bauman, Patrick Seeling
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Field experimentation, Naval Postgraduate School, Background [PDF]
, 2014 Since 2002, the Naval Postgraduate School's (NPS) Field Experimentation (FX) events have been conducted such that maximum innovation and collaboration are encouraged between DoD, government agencies, industry, universities, and in which Special ...
core +2 more sources
Studia Universitatis Moldaviae: Stiinte Sociale, 2011 Improvements in medicine and surgery during the last two centuries have greatly extended the average lifetime of people and reduced the pain and disability following various injuries and diseases.
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