Results 71 to 80 of about 7,831,859 (299)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
South African Journal of Physiotherapy, 1981 An extensive literature survey is summarised. Experimentation consisted of irradiation of paraffin wax and human subjects with microwave of frequency 2 450 MHz Results, conclusions and recommendations are briefly stated. A full reference list is given.
L. Hayward, A. Statham
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
IN THE NAME OF SCIENCE: A HISTORY OF SECRET PROGRAMS, MEDICAL RESEARCH, AND HUMAN EXPERIMENTATION
, 2003 Introduction -- Ch. 1. The chemical revolution: bringing bad things to life -- Ch. 2. Nature's weapons: man and biological warfare -- Ch. 3. The eugenics movement: past, present, and future -- Ch. 4. Human radiation experiments -- Ch. 5. The CIA and
Goliszek, Andrew
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Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Do We Need Another Advisory Commission on Human Experimentation?
, 1995 Instead of another federal advisory panel to identify ethical principles governing human subjects research, it is time we had a national board with authority to regulate and review such ...
Katz, Jay
core +1 more source
RELIEF, Research & Experimentation for Local & International Emergency & First-Responders 11-4 Experimentation: 3-5 August, 2011 [PDF]
, 2011 BLoCS Gen III Lightweight Sustainment System DynglobalNPS Field Experimentation Cooperative; Research and Experimentation for Local and International Emergency First Responders; (RELIEF) 11-04 BLoCS Gen III Lightweight Sustainment ...
Trusso, Neil
core +2 more sources
Fafnir, 2014 This article analyzes two novels by the British writer Simon Ings, Hot Head (1992) and Hotwire (1995), from perspectives provided by second-order systems theory, philosophy of neuroscience and posthumanist philosophy. In Ings' cyberpunk fiction, the use
Kaisa Kortekallio
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2002 Introduction -- Ch. 1. Embryonic stem cell research is beneficial / National Institutes of Health -- Ch. 2. Human embryo experimentation can be morally justifiable / Michael J. Meyer and Lawrence J. Nelson -- Ch. 3.
Espejo, Roman, ed.
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