Results 71 to 80 of about 208,116 (260)

Visual Interface Evaluation for Wearables Datasets: Predicting the Subjective Augmented Vision Image QoE and QoS

Future Internet, 2017
As Augmented Reality (AR) applications become commonplace, the determination of a device operator’s subjective Quality of Experience (QoE) in addition to objective Quality of Service (QoS) metrics gains importance. Human subject experimentation is common
Brian Bauman, Patrick Seeling
doaj   +1 more source

Ethics of Human Experimentation [PDF]

BMJ, 1964
B M, BENNETT, E, NAKAMURA
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

CERCETAREA ŞI EXPERIMENTUL BIOMEDICAL CA VARIANTE-TIP ALE RISCULUI MEDICAL PROFESIONAL: EXPUNEREA CONDIŢIILOR DE LEGALITATE

Studia Universitatis Moldaviae: Stiinte Sociale, 2011
Improvements in medicine and surgery during the last two centuries have greatly extended the average lifetime of people and reduced the pain and disability following various injuries and diseases.
USM ADMIN
doaj  

BEHAVIOR OF HUMAN‐IMPRINTED AND HEN‐REARED WILD TURKEY POULTS

Wildlife Society Bulletin, 1975
Behavior patterns are described for human‐imprinted and hen‐reared wild turkey poults (Meleagris gallopavo silvestris) from hatching until 4 months of age. Poults fed primarily on insects during the first 5 weeks of life.
William M. Healy, Richard O. Kimmel, Ellen J. Goetz   +2 more
doaj   +1 more source

Combining Mathematical Models With Experimentation to Drive Novel Mechanistic Insights Into Macrophage Function

Frontiers in Immunology, 2019
This perspective outlines an approach to improve mechanistic understanding of macrophages in inflammation and tissue homeostasis, with a focus on human inflammatory bowel disease (IBD).
Joanneke E. Jansen, Joanneke E. Jansen, Eamonn A. Gaffney, Jonathan Wagg, Mark C. Coles   +4 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

How to optimize communication about animal and animal-free research methods

Frontiers in Veterinary Science
There is a long-standing debate about experimental non-human animals and animal-free methods in scientific research. Among the various stakeholders involved in the debate are the scientists.
Judith Regina Homberg, Aldert H. Piersma, Aldert H. Piersma, Cyrille A. M. Krul, Lisa Genzel, Anne Kienhuis, Ellen ter Gast, Monique Wolvekamp   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source