Results 61 to 70 of about 7,831,859 (299)

Animal Experimentation Ethics Committee B

open access: yes, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University of Melbourne. Animal Experimentation Ethics Committee
core  

Jak (nie) pisać dużo? Założenia sprzeciwu wobec późnokapitalistycznej akademii a genealogie pisarstwa antropologicznego

open access: yesTeksty Drugie, 2023
The author indicates a writer’s and anthropological self-awareness that can be constructed in opposition to the neoliberal management of humanities, namely against recommendations to “write a lot.” Therefore, the article presents ways of writing and ...
Tomasz Rakowski
doaj  

Virtual commander’s operational decision-making model based on thinking simulation [PDF]

open access: yesZhihui kongzhi yu fangzhen
Focusing on the urgent need of joint operational plan simulation experimentation, aiming at the lack of intelligent decision-making ability of command entity in the current joint operations simulation systems, and the difficulty of popularizing the ...
JIA Chenxing, MING Yuewei, GE Chenglong
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Animal Experimentation Ethics Committee A

open access: yes, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University of Melbourne. Animal Experimentation Ethics Committee
core  

INTELIGENCIA ARTIFICIAL HÍBRIDA. UNA AMENAZA A LATINOAMÉRICA

open access: yesRevistas Argentina de Medicina, 2018
En el último tiempo existe una gran promoción de la llamada inteligencia artificial híbrida, la fusión de nuestro cerebro con implantes cerebrales. Se afirma que la inteligencia artificial híbrida es un beneficio para la sociedad; sin embargo, no se ...
David Salinas Flores
doaj   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The Effects of Human Behavior Simulation on Architecture Major Students′ Fire Egress Planning

open access: yesJournal of Asian Architecture and Building Engineering, 2018
This study examines the previously unknown relationship between using human behavior simulation, equipped autonomous, intelligent Virtual-Users, and students′ self-experimentation performance in fire egress planning.
Seung Wan Hong, Yun Gil Lee
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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