Results 61 to 70 of about 741,034 (292)

Physician-Patient Relationship

open access: yesVoices in Bioethics, 2013
Hannibal. Just saying the name sends chills down the spine and piques the curiosity of the small part of you that asks “What if...” NBC’s thriller television series “Hannibal”  astonished viewers worldwide with its beautiful cinematography ...
Jhia Louise Jackson
doaj   +1 more source

Psychophysical Research in Development of a Fiber-optic Helmet Mounted Display [PDF]

open access: yes, 1984
The Fiber Optic Helmet Mounted Display (FOHMD) was conceived as an innovative solution to existing flight simulator display deficiencies. An initial (breadboard) version of the system was fabricated to permit experimentation which would help define ...
Kruk, R. V., Longridge, T. M.
core   +1 more source

Affect Recognition in Ads with Application to Computational Advertising [PDF]

open access: yes, 2017
Advertisements (ads) often include strongly emotional content to leave a lasting impression on the viewer. This work (i) compiles an affective ad dataset capable of evoking coherent emotions across users, as determined from the affective opinions of five
Gullapuram, Shruti Shriya   +5 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Jak (nie) pisać dużo? Założenia sprzeciwu wobec późnokapitalistycznej akademii a genealogie pisarstwa antropologicznego

open access: yesTeksty Drugie, 2023
The author indicates a writer’s and anthropological self-awareness that can be constructed in opposition to the neoliberal management of humanities, namely against recommendations to “write a lot.” Therefore, the article presents ways of writing and ...
Tomasz Rakowski
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

INTELIGENCIA ARTIFICIAL HÍBRIDA. UNA AMENAZA A LATINOAMÉRICA

open access: yesRevistas Argentina de Medicina, 2018
En el último tiempo existe una gran promoción de la llamada inteligencia artificial híbrida, la fusión de nuestro cerebro con implantes cerebrales. Se afirma que la inteligencia artificial híbrida es un beneficio para la sociedad; sin embargo, no se ...
David Salinas Flores
doaj   +2 more sources

Virtual commander’s operational decision-making model based on thinking simulation [PDF]

open access: yesZhihui kongzhi yu fangzhen
Focusing on the urgent need of joint operational plan simulation experimentation, aiming at the lack of intelligent decision-making ability of command entity in the current joint operations simulation systems, and the difficulty of popularizing the ...
JIA Chenxing, MING Yuewei, GE Chenglong
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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