Results 51 to 60 of about 207,063 (262)
Physician-Patient Relationship
Voices in Bioethics, 2013 Hannibal. Just saying the name sends chills down the spine and piques the curiosity of the small part of you that asks “What if...” NBC’s thriller television series “Hannibal” astonished viewers worldwide with its beautiful cinematography ...
Jhia Louise Jackson
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
INTELIGENCIA ARTIFICIAL HÍBRIDA. UNA AMENAZA A LATINOAMÉRICA
Revistas Argentina de Medicina, 2018 En el último tiempo existe una gran promoción de la llamada inteligencia artificial híbrida, la fusión de nuestro cerebro con implantes cerebrales. Se afirma que la inteligencia artificial híbrida es un beneficio para la sociedad; sin embargo, no se ...
David Salinas Flores
doaj +2 more sources
Teksty Drugie, 2023 The author indicates a writer’s and anthropological self-awareness that can be constructed in opposition to the neoliberal management of humanities, namely against recommendations to “write a lot.” Therefore, the article presents ways of writing and ...
Tomasz Rakowski
doaj
Virtual commander’s operational decision-making model based on thinking simulation [PDF]
Zhihui kongzhi yu fangzhenFocusing on the urgent need of joint operational plan simulation experimentation, aiming at the lack of intelligent decision-making ability of command entity in the current joint operations simulation systems, and the difficulty of popularizing the ...
JIA Chenxing, MING Yuewei, GE Chenglong
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The Effects of Human Behavior Simulation on Architecture Major Students′ Fire Egress Planning
Journal of Asian Architecture and Building Engineering, 2018 This study examines the previously unknown relationship between using human behavior simulation, equipped autonomous, intelligent Virtual-Users, and students′ self-experimentation performance in fire egress planning.
Seung Wan Hong, Yun Gil Lee
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source