Results 41 to 50 of about 8,775,558 (296)

Biomedical researches and ethics

open access: yesCerrahpaşa Medical Journal, 2014
The parallel faced problems since 20th century; topics of science, research and publication ethics have been started to take seriously nowadays. Especially in biomedical field, lots of historical examples for “putting society’s benefits before the ...
Gülten DİNÇ
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Nature and Context of Exploratory Experimentation: An Introduction to Three Case Studies of Exploratory Research [PDF]

open access: yes, 2007
: My aim in this article is to introduce readers to the topic of exploratory experimentation and briefly explain how the three articles that follow, by Richard Burian, Kevin Elliott, and Maureen O’Malley advance our understanding of the nature and ...
Waters, C. Kenneth
core  

Towards Algorithms for Autonomous Experimentation

open access: yes, 2009
1 Introduction Modelling biological systems, is impaired by the cost of experimentally obtaining the data required to build the models. The resources available are typically very limited compared to large experimental parameter spaces, so have to be used
Lovell, C. J., Zauner, K.-P.
core   +1 more source

“PEI-ICF PETRA”: a smart web platform to foster cooperation in drafting the individualized Education Plan (IEP) for students with disability

open access: yesCogent Education
The implementation of the framework offered by the international classification of functioning disability and health (ICF) is recognized as a necessary step in the process of school inclusion for pupils with disabilities.
C. Scapin   +5 more
doaj   +1 more source

Human exhaled air energy harvesting with specific reference to PVDF film

open access: yesEngineering Science and Technology, an International Journal, 2017
Spirometer is a medical equipment used to measure lung capacity of a human being. It leads to diagnosis of several diseases. The researchers worked on harvesting energy from human exhalation while carrying out measurements using spirometer.
Manisha Rajesh Mhetre   +1 more
doaj   +1 more source

Human Experimentation and Human Rights*

open access: yes, 2017
ion of the research question tends to objectify the person-patient.27 It does so to a significantly greater extent than in therapeutic interactions, even though similar problems of objectification arise in therapeutic settings when doctors attend too much to the disease of the body in the bed and not to the person before them.
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Animals in Moral Limbo: How Literary Pigs May Help Lab-Generated Ones

open access: yesAnimals, 2020
When considering that artistic and literary artifacts reflect the cultural views and mores of a particular time period, there is a significant misalignment between stories depicting increased moral status of pigs (e.g., vis-à-vis human-porcine ...
Nancy Tuck
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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