Results 41 to 50 of about 741,034 (292)

“PEI-ICF PETRA”: a smart web platform to foster cooperation in drafting the individualized Education Plan (IEP) for students with disability

open access: yesCogent Education
The implementation of the framework offered by the international classification of functioning disability and health (ICF) is recognized as a necessary step in the process of school inclusion for pupils with disabilities.
C. Scapin   +5 more
doaj   +1 more source

Human exhaled air energy harvesting with specific reference to PVDF film

open access: yesEngineering Science and Technology, an International Journal, 2017
Spirometer is a medical equipment used to measure lung capacity of a human being. It leads to diagnosis of several diseases. The researchers worked on harvesting energy from human exhalation while carrying out measurements using spirometer.
Manisha Rajesh Mhetre   +1 more
doaj   +1 more source

Animals in Moral Limbo: How Literary Pigs May Help Lab-Generated Ones

open access: yesAnimals, 2020
When considering that artistic and literary artifacts reflect the cultural views and mores of a particular time period, there is a significant misalignment between stories depicting increased moral status of pigs (e.g., vis-à-vis human-porcine ...
Nancy Tuck
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

A Monoclonal Human Alveolar Epithelial Cell Line (“Arlo”) with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections

open access: yesAdvanced Science, 2023
In the development of orally inhaled drug products preclinical animal models regularly fail to predict pharmacological as well as toxicological responses in humans.
Patrick Carius   +15 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Murky Projects and Uneven Information Policies: A Case Study of the Psychological Strategy Board and CIA

open access: yesSecrecy and Society, 2018
This case study discusses the Truman and Eisenhower administration's (1951-1953) short-lived Psychological Strategy Board (PSB). Through the lens of declassified documents, the article recounts the history and activities of the Board, including its ...
Susan Maret
doaj  

Impact of Architectural Forms on Human PerceptionA Neurocognitive Experimentation

open access: yesProceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA
The form or shape of the built environment is fundamental to architectural design, but not many studies have shown the impact of different forms on the inhabitants’ consciousness.
Abhijeet Pal, Ammar Ul Haq
doaj   +1 more source

The use of Human Subjects in Biomedical Research: A Problematic Scientific Past Shapes Present Ethical Challenges [PDF]

open access: yes, 2012
The ethics of human experimentation is a relatively new phenomenon in medicine. The Nuremberg Code and the Helsinki Declaration focused on informed consent in human experimentation.
Pawlik, Timothy M.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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