Results 31 to 40 of about 8,775,558 (296)

RELIEF, Research & Experimentation for Local & International Emergency & First-Responders 11-4 Experimentation: 3-5 August, 2011 [PDF]

open access: yes, 2011
BLoCS Gen III Lightweight Sustainment System DynglobalNPS Field Experimentation Cooperative; Research and Experimentation for Local and International Emergency First Responders; (RELIEF) 11-04 BLoCS Gen III Lightweight Sustainment ...
Trusso, Neil
core   +2 more sources

Compreensão do termo de consentimento em pesquisa clínica

open access: yesRevista Bioética
Resumo O termo de consentimento livre e esclarecido (TCLE) é documento onde se explicita o consentimento do participante, contendo todas as informações necessárias para que seja elucidada a pesquisa da qual se propõe participar. O objetivo deste trabalho
Clarissa de Assumpção   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Ups and Downs of the Declaration of Helsinki: The Case of the Placebo

open access: yesPerspectivas Metodológicas​
The Declaration of Helsinki, adopted in 1964 by the World Medical Association, is an ethical benchmark for research involving human subjects. Throughout its successive revisions, it has faced debates and controversies around several of its articles. This
María Fernanda Sabio
doaj   +1 more source

The scientific imperative: why human-centered models must replace animal experimentation? [PDF]

open access: yesBrazilian Journal of Biology
This paper aims to deconstruct the ethical and scientific impasse of using animals in biomedical research by proposing a paradigm shift towards human-centered methodologies.
Iván Vargas-Chaves
doaj   +1 more source

The ethics of AI-assisted warfighter enhancement research and experimentation: Historical perspectives and ethical challenges

open access: yesFrontiers in Big Data, 2022
The military applications of AI raise myriad ethical challenges. Critical among them is how AI integrates with human decision making to enhance cognitive performance on the battlefield.
Jonathan Moreno   +5 more
doaj   +1 more source

Experimental renewal in human participants.

open access: yesJournal of Experimental Psychology: Animal Behavior Processes, 2011
Two experiments with human participants are presented that differentiate renewal from other behavioral effects that can produce a response after extinction. Participants played a video game and learned to suppress their behavior when sensor stimuli predicted an attack.
James Byron Nelson   +4 more
openaire   +5 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Human-structure interaction: experimentation and modelling for vertical vibration

open access: yes, 2018
Experimentation and modelling of human-structure interaction for vertical vibration were conducted. HSI existence and its effect were identified. A moving spring-mass-damper model was calibrated and validated against the experimental data to account for ...
EHSAN AHMADI (5363165)
core   +1 more source

An Artificial Experimenter for Enzymatic Response Characterisation

open access: yes, 2010
Identifying the characteristics of biological systems through physical experimentation, is restricted by the resources available, which are limited in comparison to the size of the parameter spaces being investigated.
Zauner, Klaus-Peter   +3 more
core   +2 more sources

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