Results 121 to 130 of about 18,923,181 (308)

The physiological foundation of extinction improvement by tDCS over the ventromedial prefrontal cortex (vmPFC) in healthy humans: an fMRI study

Translational Psychiatry
A growing body of research highlights the fear extinction model as a key framework for understanding the pathology of anxiety disorders and developing therapeutic interventions.
Harleen Chhabra, Yuanbo Ma, Erhan Genç, Michael A. Nitsche, Fatemeh Yavari   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Human factors design guide update (report number DOT/FAA/CT-96/01) : a revision to chapter 5--automation guidelines. [PDF]

This document contains an updated and expanded version of the Automation chapter of the Human Factors Design Guide. A researchteam of human factors experts evaluated the existing guidelines for relevance, clarity, and usability. The research team drafted
Truitt, Todd R, Titan Systems Corporation, Longo, Kelly, Ahlstrom, Vicki, William J. Hughes Technical Center (U.S.)   +4 more
core  

Patient-Centric Design of the Lonapegsomatropin Auto-Injector for Growth Hormone Deficiency: Usability Validation of Safe and Effective Use

Medical Devices: Evidence and Research
Michael Lau,1 Paul Erik Fabricius,2 Nils Berg Madsen,3 Henrik Egesborg,3 Josephine Jensen3 1Human Factors Engineering, Insight by Nemera, Chicago, IL, USA; 2Industrial Design and HFE, Phillips-Medisize A/S, Struer, Denmark; 3Device Development, Ascendis ...
Lau M, Fabricius PE, Madsen NB, Egesborg H, Jensen J   +4 more
doaj  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Evaluation of Ohio Department of Transportation roadway/weather sensor systems for snow and ice removal operations. Part I, RWIS

, 2003
"June 2003."; Includes bibliographical references (p. 107-113).; Final report.; Performed by Human Factors and Ergonomics Laboratory, Ohio Research Institute for Transportation and the Environment for Ohio Dept.
Zwahlen, Helmut T., Ohio Research Institute for Transportation and the Environment. Human Factors and Ergonomics Laboratory.   +1 more
core  

Induction and stabilization of brain oscillations in delta frequency by phase-synchronized rTMS and tACS

Brain Stimulation, 2023
Kuri Takahashi, Benedikt Glinski, Mohammad Ali Salehinejad, Min-Fang Kuo, Michael Nitsche   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

NMDA receptor–related mechanisms of dopaminergic modulation of tDCS-induced neuroplasticity

Brain Stimulation, 2023
Elham Ghanavati, Mohammad Ali Salehinejad, Lorena De Melo, Michael A. Nitsche, Min-Fang Kuo   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source