Results 121 to 130 of about 26,756,178 (360)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Connecting Pathogen Transmission and Performance of the WHO’s ‘My 5 Moments of Hand Hygiene’ in a High-Fidelity Simulation

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: The World Health Organization launched ‘Your 5 moments for hand hygiene’ to identify when healthcare workers should perform hand hygiene to reduce healthcare-associated infections (HAIs).
Paige Gannon   +9 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Knowing when to support: a human-aware agent model in a psychological domain

open access: yes, 2016
The human mind is undoubtedly one of the most complicated entities in this world. The collection of processes that are performed by the human mind is indicated by cognition.
JawatanKuasa Kerja PSM Human Factors and Ergonomics Society Malaysia
core  

We Don���t Learn Enough from Incidents: the Roots of Human Errors [PDF]

open access: yes, 2019
PresentationProcess Safety aims to prevent and control incidents that have the potential to release hazards that could result in serious undesired outcomes. It has been widely agreed for some time now that human error is a causal factor in most accidents.
Philippart, M��nica
core  

Human factors within paramedic practice: the forgotten paradigm

open access: yes, 2010
It would seem hard to imagine how you could draw a comparison between a commercial airline pilot struggling to land a stricken plane in a storm and a paramedic fighting to save the life of a patient in cardiac arrest.
Summers, Andy, Willis, Sam
core   +1 more source

Synchronization-based fusion of EEG and eye blink signals for enhanced decoding accuracy

open access: yesScientific Reports
Decoding locomotor tasks is crucial in cognitive neuroscience for understanding brain responses to physical tasks. Traditional methods like EEG offer brain activity insights but may require additional modalities for enhanced interpretative precision and ...
Emad Alyan   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ITKids: Is paper IT work more physically variable than computer IT work for children?

open access: yes, 2007
Children are spending more time than ever on computers for school and leisure and the effect of computer use on their developing musculoskeletal systems is of concern.
Burgess-Limerick, Robin   +7 more
core  

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