Results 301 to 310 of about 2,026,261 (344)

Disease coverage of human genome-wide association studies and pharmaceutical research and development. [PDF]

Commun Med (Lond)
Gordillo-Marañón M, Schmidt AF, Warwick A, Tomlinson C, Ytsma C, Engmann J, Torralbo A, Maclean R, Sofat R, Langenberg C, Shah AD, Denaxas S, Pirmohamed M, Hemingway H, Hingorani AD, Finan C.   +15 more
europepmc   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

G-quadruplexes as pivotal components of cis-regulatory elements in the human genome. [PDF]

BMC Biol
Zhang R, Wang Y, Wang C, Sun X, Mergny JL.   +4 more
europepmc   +1 more source

Endogenous retroviral solo-LTRs in human genome. [PDF]

Front Genet
Chen M, Huang X, Wang C, Wang S, Jia L, Li L.   +5 more
europepmc   +1 more source

Heritable human genome editing: correction, selection and treatment. [PDF]

Med Law Rev
Scott R.
europepmc   +1 more source

Microsatellite density landscapes illustrate short tandem repeats aggregation in the complete reference human genome. [PDF]

BMC Genomics
Xia Y, Li D, Chen T, Pan S, Huang H, Zhang W, Liang Y, Fu Y, Peng Z, Zhang H, Zhang L, Peng S, Shi R, He X, Zhou S, Jiao W, Zhao X, Wu X, Zhou L, Zhou J, Ouyang Q, Tian Y, Jiang X, Zhou Y, Tang S, Shen J, Ohshima K, Tan Z.   +27 more
europepmc   +1 more source

Challenging the Boundaries Between Treatment, Prevention, and Enhancement in Human Genome Editing. [PDF]

CRISPR J
Waltz M, Walker RL, Flatt MA, MacKay D, Conley JM, Juengst ET, Cadigan RJ.   +6 more
europepmc   +1 more source

Minimal twister sister-like self-cleaving ribozymes in the human genome revealed by deep mutational scanning. [PDF]

Elife
Zhang Z, Hong X, Xiong P, Wang J, Zhou Y, Zhan J.   +5 more
europepmc   +1 more source

Ancient viral DNA in the human genome linked to neurodegenerative diseases.

Brain Behav Immun
Duarte RRR, Nixon DF, Powell TR.
europepmc   +1 more source

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The Human Genome

Science, 2001
Humanity has been given a great gift. With the completion of the human genome sequence, we have received a powerful tool for unlocking the secrets of our genetic heritage and for finding our place among the other participants in the adventure of life.
Donald Kennedy, Barbara R. Jasny
  +8 more sources