Results 311 to 320 of about 10,781,581 (397)

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Minimal twister sister-like self-cleaving ribozymes in the human genome revealed by deep mutational scanning. [PDF]

Elife
Zhang Z, Hong X, Xiong P, Wang J, Zhou Y, Zhan J.   +5 more
europepmc   +1 more source

Genome-wide maps of highly-similar intrachromosomal repeats that can mediate ectopic recombination in three human genome assemblies. [PDF]

HGG Adv
Fernandez-Luna L, Aguilar-Perez C, Grochowski CM, Mehaffey MG, Carvalho CMB, Gonzaga-Jauregui C.   +5 more
europepmc   +1 more source

Efficient manipulation of the human adenovirus genome as an infectious yeast artificial chromosome clone. [PDF]

, 1994
Gary Ketner, Forrest Spencer, Stuart Tugendreich, Carla J. Connelly, Philip Hieter   +4 more
openalex   +1 more source

Detection of large-scale variation in the human genome

Nature Genetics, 2004
A. J. Iafrate, L. Feuk, Miguel N Rivera, M. Listewnik, Patricia K. Donahoe, Y. Qi, Stephen W. Scherer, Charles Lee   +7 more
semanticscholar   +1 more source

O09: Phenome-wide studies of hereditary transthyretin amyloidosis in the All of Us research program

Genetics in Medicine Open
Cassia Williams-Rogers, Tam Tran, Caralynn Wilczewski, Felicia Akinwande, Nicholas Singh-Miller, Ashley Glasper, Yeabsira Tufa, Tracey Ferrara, Jennifer Johnston, Leslie Biesecker, Joshua Denny, Clesson Turner, Huan Mo   +12 more
doaj  

Microsatellite density landscapes illustrate short tandem repeats aggregation in the complete reference human genome. [PDF]

BMC Genomics
Xia Y, Li D, Chen T, Pan S, Huang H, Zhang W, Liang Y, Fu Y, Peng Z, Zhang H, Zhang L, Peng S, Shi R, He X, Zhou S, Jiao W, Zhao X, Wu X, Zhou L, Zhou J, Ouyang Q, Tian Y, Jiang X, Zhou Y, Tang S, Shen J, Ohshima K, Tan Z.   +27 more
europepmc   +1 more source

Unexplored therapeutic opportunities in the human genome

Nature reviews. Drug discovery, 2018
Tudor I. Oprea, C. Bologa, S. Brunak, A. Campbell, G. Gan, A. Gaulton, S. Gomez, R. Guha, A. Hersey, Jayme Holmes, A. Jadhav, L. Jensen, Gary L. Johnson, Anneli Karlson, A. Leach, Avi Ma’ayan, A. Malovannaya, S. Mani, Stephen L. Mathias, Michael T. McManus, T. Meehan, C. V. Mering, D. Muthas, Dac-Trung Nguyen, John P. Overington, G. Papadatos, J. Qin, C. Reich, B. Roth, S. Schürer, A. Simeonov, L. Sklar, Noel Southall, Susumu Tomita, Ilinca Tudose, O. Ursu, Dušica Vidovic´, A. Waller, D. Westergaard, Jeremy J. Yang, Gergely Zahoránszky-Köhalmi   +40 more
semanticscholar   +1 more source

Genetically humanized phenylketonuria mouse model as a testing tool for human genome editing in fertilized eggs. [PDF]

J Inherit Metab Dis
Tsuji-Hosokawa A, Tsuchiya I, Shimizu K, Terao M, Yasuhara M, Miyamoto N, Kikuchi S, Ogawa Y, Nakamura K, Matsubara Y, Takada S.   +10 more
europepmc   +1 more source

Peculiar k-mer Spectra Are Correlated with 3D Contact Frequencies and Breakpoint Regions in the Human Genome. [PDF]

Genes (Basel)
Hikmat WM, Sievers A, Hausmann M, Hildenbrand G.   +3 more
europepmc   +1 more source