Results 351 to 360 of about 10,781,581 (397)

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.

, 1990
Nobuyuki Kato, Makoto Hijikata, Yuko Ootsuyama, M Nakagawa, Shogo Ohkoshi, T Sugimura, Kunitada Shimotohno   +6 more
openalex   +1 more source

Concepts for a Semantically Accessible Materials Data Space: Overview over Specific Implementations in Materials Science

Advanced Engineering Materials, EarlyView.
This manuscript presents advances in digital transformation within materials science and engineering, emphasizing the role of the MaterialDigital Initiative. By testing and applying concepts such as ontologies, knowledge graphs, and integrated workflows, it promotes semantic interoperability and data‐driven innovation. The article reviews collaborative
Bernd Bayerlein, Jörg Waitelonis, Henk Birkholz, Matthias Jung, Markus Schilling, Philipp v. Hartrott, Marian Bruns, Jörg Schaarschmidt, Kristian Beilke, Marcel Mutz, Vincent Nebel, Veit Königer, Lisa Beran, Tobias Kraus, Akhilesh Vyas, Lars Vogt, Moritz Blum, Basil Ell, Ya‐Fan Chen, Tina Waurischk, Akhil Thomas, Ali Riza Durmaz, Sahar Ben Hassine, Carina Fresemann, Gordian Dziwis, Hossein Beygi Nasrabadi, Thomas Hanke, Melissa Telong, Stephan Pirskawetz, Mohamed Kamal, Thomas Bjarsch, Ursula Pähler, Peter Hofmann, Mena Leemhuis, Özgür L. Özçep, Lars‐Peter Meyer, Birgit Skrotzki, Jörg Neugebauer, Wolfgang Wenzel, Harald Sack, Chris Eberl, Pedro Dolabella Portella, Tilmann Hickel, Lutz Mädler, Peter Gumbsch   +44 more
wiley   +1 more source

Amplification‐Free, Sequencing‐Free, Detection of Viral RNAs with Variant Specification by Discrete Nanocounting

Advanced Functional Materials, EarlyView.
Integrating selective RNA shortcut, targeted gene isolation, and micro‐arrayed nanoimaging, the NanoPick‐array platform excels in detecting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) at just 60 copies µL−1 and accurately differentiating variants at the single‐nucleotide level. It ensures 100% accuracy for samples with cycle threshold (
Zixun Wang, Xi Zhao, Wan‐Mui Chan, Xianglin Ji, Linfeng Huang, Xi Xie, Wei Li, Wenjun Zhang, Kelvin Kai‐Wang To, Peng Shi   +9 more
wiley   +1 more source

Editorial: The impact of the human genome on interindividual variability in drug response. [PDF]

Front Genet
Kassogue Y, Fricke-Galindo I.
europepmc   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

Context-adjusted proportion of singletons (CAPS): a novel metric for assessing negative selection in the human genome. [PDF]

NAR Genom Bioinform
Gudkov M, Thibaut L, Giannoulatou E.
europepmc   +1 more source

Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics

Advanced Functional Materials, EarlyView.
Designer DNA Architecture‐templated Drug Conjugates (DDA‐DCs) are comprised of a DNA nanomaterial decorated with multiple drug‐loaded DNA aptamers. DDA‐DCs use a combination of multiple aptamer types, each recognizing a different membrane protein to achieve precise targeting of cancer cells.
Abhisek Dwivedy, Dhyanesh Baskaran, Gaurav Sharma, Wei Hong, Dhanush Gandavadi, Abhichart Krissanaprasit, Joonsu Han, Yusheng Liu, Zack Zimmers, Tshepo Mafokwane, Ichrak Hayah, Neha Chauhan, Mengxi Zheng, Sherwood Yao, Keith Fraser, John S. Decker, Xiaohe Jin, Hua Wang, Adam D. Friedman, Xing Wang   +19 more
wiley   +1 more source

Biomimetic Co‐delivery of Lenvatinib and FePt Nanoparticles for Enhanced Ferroptosis/Apoptosis Treatment of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
This study introduces a novel HCC treatment using poly lactic‐co‐glycolic acid (PLGA) nanoparticles encased in HCC cell membranes to co‐deliver Lenvatinib and FePt nanoparticles. This approach improves treatment efficacy by enhancing ferroptosis and apoptosis.
Feichao Xuan, Xingyang Zhao, Weiran Pang, Zirong Li, Xiangyi Yin, Weizhong Xie, Xiaojun Zeng, Liming Nie, Junying Yang, Shiying Li, Puxiang Lai, Chihua Fang   +11 more
wiley   +1 more source

Computational identification of ultra-conserved elements in the human genome: a hypothesis on homologous DNA pairing. [PDF]

NAR Genom Bioinform
Crossley ER, Fedorova L, Mulyar OA, Freeman R, Khuder S, Fedorov A.   +5 more
europepmc   +1 more source

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

Advanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han, Godfrey Mwiti, Seo‐Joon Yeom, Jaeyoon Lim, Woo Sik Kim, Sangyong Lim, Seung‐Taik Lim, Eui‐Baek Byun   +7 more
wiley   +1 more source