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Assays for human growth hormones

Journal of Pharmaceutical and Biomedical Analysis, 1989
Human growth hormone is, in effect, defined by its activity in an in vivo bioassay and the standard used with it, growth being measured as the increase in body weight in hypophysectomised immature rats. The assay reflects the hormone's survival and metabolism in vivo, its cell-cell interactions, the activation and effects of its secondary hormones ...
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Growth Hormone in Human Development

Nature, 1968
MANY investigators have established that changes occur in the structure of enzymes and other proteins during development. For example, Cahn et al. have shown changes in the isoenzymes of lactic dehydrogenase (LDH)1, and Korber was the first to recognize that foetal haemoglobin is more resistant to alkali than maternal haemoglobin2.
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Biosynthetic Human Growth Hormone in the Treatment of Growth Hormone Deficiency

Acta Paediatrica, 1990
ABSTRACT. A total of 309 previously untreated children with growth hormone deficiency (GHD) (219 boys, 90 girls; mean age 8.4 ± 3.9 years, range 1.5‐19 years) were treated for up to 3 years in an ongoing trial designed to examine the long‐term efficacy and safety of biosynthetic somatropin (rhGH).
P M Conforti   +4 more
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EFFECTS OF HUMAN GROWTH HORMONE ON THE SECRETION OF RAT GROWTH HORMONE

Journal of Endocrinology, 1980
Human growth hormone (hGH) was administered to chronically cannulated male rats and its effect upon the physiological secretory patterns of rat growth hormone (rGH) and prolactin were observed. In comparison with injected control animals, a reduction in the size of spontaneous secretory bursts of rGH was apparent when hormone concentrations were ...
M. F. Menadue   +4 more
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Human growth hormone release in sleep: effect of daytime exercise.

Journal of Clinical Endocrinology and Metabolism, 1971
Slow-wave sleep and human growth hormone release in early sleep was studied in 10 normal subjects after graded daytime exercise. Only 4 of 10 subjects had greater postexercise slow-wave sleep and only 2 of 10 subjects had augmented post-exercise sleep ...
L. Zir, R. A. Smith, D. Parker
semanticscholar   +1 more source

Human Growth Hormone

2012
On the mental level there was improved mental concentration and mental clarity. Vivid dreams. Increased appetite. Nasal congestion. Ulcerations in the mouth. Cramping pains in various parts of the body.
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Human growth hormone levels in cerebrospinal fluid.

Journal of Clinical Endocrinology and Metabolism, 1970
Nine patients with uncomplicated acromegaly showed the cerebrospinal fluid (CSF) human growth hormone (HGH) to be 0.49±0.11 ng/ml (mean±sem) as compared to 8 control subjects whose values were extremely low (
John A. Linfoot   +6 more
semanticscholar   +1 more source

The Human Liver Growth Hormone Receptor*

Endocrinology, 1989
Human livers, obtained from donors at the time of transplant, were homogenized in 0.25 M sucrose and fractionated by differential centrifugation. The specific binding of [125I] human (h) GH to total particulate fractions from 18 livers varied from 0.4-5.1% of the total radioactivity/100 micrograms protein.
Hocquette, Jean-François   +4 more
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Metabolic effects of human growth hormone and growth hormone of other species in man.

, 1960
The metabolic effects of human growth hormone were investigated under varied clinical conditions in 15 balance studies on 10 subjects. Nitrogen retention occurred uniformly, the amount varying from 2 to 4 Gm. daily. Potassium and phosphorus were likewise
D. Bergenstal, M. Lipsett
semanticscholar   +1 more source

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