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Rejuvenating the human gut microbiome
Trends in Molecular Medicine, 2022Industrial advances have caused significant loss of diversity in our gut microbiome, potentially increasing our susceptibility to many diseases. Recently, rewilding the human gut microbiome - that is, bringing it back to an ancestral or preindustrial state (e.g., by transplanting stool material from donors in nonindustrial societies) - has been hotly ...
Shanlin Ke, Scott T. Weiss, Yang-Yu Liu
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Metagenome of human gut virome and human gut microbiota
2022Metagenome of human gut virome and human gut ...
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2016
The microbiota in our gut performs many different essential functions that help us to stay healthy. These functions include vitamin production, regulation of lipid metabolism and short chain fatty acid production as fuel for epithelial cells and regulation of gene expression.
Harmsen, Hermie J. M. +1 more
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The microbiota in our gut performs many different essential functions that help us to stay healthy. These functions include vitamin production, regulation of lipid metabolism and short chain fatty acid production as fuel for epithelial cells and regulation of gene expression.
Harmsen, Hermie J. M. +1 more
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Human Gut Microbiome: Function Matters
Trends in Microbiology, 2018The human gut microbiome represents a complex ecosystem contributing essential functions to its host. Recent large-scale metagenomic studies have provided insights into its structure and functional potential. However, the functional repertoire which is actually contributed to human physiology remains largely unexplored. Here, by leveraging recent omics
Anna, Heintz-Buschart, Paul, Wilmes
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The FASEB Journal, 2016
The human large bowel is colonized by a community of microbes, the microbiota, which has a significant impact on human health and nutrition through the production of short chain fatty acids (SCFAs), and by interaction with the host immune system. The major nutrients available to these organisms are dietary glycans, also known as complex carbohydrates ...
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The human large bowel is colonized by a community of microbes, the microbiota, which has a significant impact on human health and nutrition through the production of short chain fatty acids (SCFAs), and by interaction with the host immune system. The major nutrients available to these organisms are dietary glycans, also known as complex carbohydrates ...
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Coarse graining the human gut microbiome
Cell Host & Microbe, 2023The composition of the human gut microbiome is heterogeneous across people. However, if you squint, co-abundant microbial genera emerge, accounting for much of this ecological variability. In this issue of Cell Host & Microbe, Frioux et al. provide a workflow for identifying these bacterial guilds, or "enterosignatures."
Christian Diener, Sean M. Gibbons
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Neurogastroenterology & Motility, 1993
AbstractIn recent years, new neurophysiological techniques have been developed which allow access to the gut‐brain axis in humans. Among these tools, recording of cerebral evoked potentials following stimulation of a viscera (rectosigmoid, oesophagus) as well as the striated anal sphincter muscle have gained importance for evaluation of afferent ...
P. ENCK, T. FRIELING
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AbstractIn recent years, new neurophysiological techniques have been developed which allow access to the gut‐brain axis in humans. Among these tools, recording of cerebral evoked potentials following stimulation of a viscera (rectosigmoid, oesophagus) as well as the striated anal sphincter muscle have gained importance for evaluation of afferent ...
P. ENCK, T. FRIELING
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The shrinking human gut microbiome
Current Opinion in Microbiology, 2017Mammals harbor complex assemblages of gut bacteria that are deeply integrated with their hosts' digestive, immune, and neuroendocrine systems. Recent work has revealed that there has been a substantial loss of gut bacterial diversity from humans since the divergence of humans and chimpanzees.
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Carbohydrates and the human gut microbiota
Current Opinion in Clinical Nutrition and Metabolic Care, 2013Due to its scale and its important role in maintaining health, the gut microbiota can be considered as a 'new organ' inside the human body. Many complex carbohydrates are degraded and fermented by the human gut microbiota in the large intestine to both yield basic energy salvage and impact gut health through produced metabolites.This review will focus ...
Chassard, Christophe +1 more
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Metagenomics: Key to Human Gut Microbiota
Digestive Diseases, 2011The human gastrointestinal tract harbors the most complex human microbial ecosystem (intestinal microbiota). The comprehensive genome of these microbial populations (intestinal microbiome) is estimated to have a far greater genetic potential than the human genome itself. Correlations between changes in composition and activity of the gut microbiota and
MACCAFERRI, SIMONE +2 more
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