Results 11 to 20 of about 78,351 (172)

The Human Gut Virome and Its Relationship with Nontransmissible Chronic Diseases. [PDF]

Nutrients, 2023
The human gastrointestinal tract contains large communities of microorganisms that are in constant interaction with the host, playing an essential role in the regulation of several metabolic processes.
Ezzatpour S, Mondragon Portocarrero ADC, Cardelle-Cobas A, Lamas A, López-Santamarina A, Miranda JM, Aguilar HC.   +6 more
europepmc   +4 more sources

Uncovering novel human gut virome using ultra-deep metagenomic sequencing. [PDF]

Chin Med J (Engl), 2022
Human gastrointestinal tract harbors trillions of commensal microbes including bacteria, viruses, and fungi to form an ecological community, commonly known as the gut microbiome.
Lau HCH, Yu J.
europepmc   +5 more sources

Characterization of the human gut virome in metabolic and autoimmune diseases. [PDF]

Inflamm Regen, 2022
The intestinal microbiome is dominated by bacteria and plays a pivotal role in the occurrence and development of disease, including several metabolic and autoimmune disorders.
Fujimoto K, Miyaoka D, Uematsu S.
europepmc   +5 more sources

Profiling of Human Gut Virome with Oxford Nanopore Technology

Medicine in Microecology, 2020
Human gut virome play critical roles in maintaining gut microbial composition and functionality, as well as host physiology and immunology. Yet, there are insufficient amount of studies on this topic mainly due to methodological limitations, including ...
Jiabao Cao, Yuqing Zhang, Min Dai, Jiayue Xu, Liang Chen, Faming Zhang, Na Zhao, Jun Wang   +7 more
doaj   +3 more sources

Bacteriophages of the Order Crassvirales: What Do We Currently Know about This Keystone Component of the Human Gut Virome? [PDF]

Biomolecules, 2023
The order Crassvirales comprises dsDNA bacteriophages infecting bacteria in the phylum Bacteroidetes that are found in a variety of environments but are especially prevalent in the mammalian gut.
Smith L, Goldobina E, Govi B, Shkoporov AN.   +3 more
europepmc   +2 more sources

Structural and Functional Disparities within the Human Gut Virome in Terms of Genome Topology and Representative Genome Selection. [PDF]

Viruses, 2023
Circularity confers protection to viral genomes where linearity falls short, thereby fulfilling the form follows function aphorism. Yet, a shift away from morphology-based classification towards molecular and ecological classification of viruses is ...
Veldsman WP, Yang C, Zhang Z, Huang Y, Chowdhury D, Zhang L.   +5 more
europepmc   +2 more sources

The gut virome and human health: From diversity to personalized medicine

Engineering Microbiology
The human gut virome plays a crucial role in the gut and overall health; its diversity and regulatory functions influence bacterial populations, metabolism, and immune responses.
Rahul Harikumar Lathakumari, Leela Kakithakara Vajravelu, Anusha Gopinathan, Poornima Baskar Vimala, Vishnupriya Panneerselvam, Sujith Sri Surya Ravi, Jayaprakash Thulukanam   +6 more
doaj   +3 more sources

The genetic diversity and populational specificity of the human gut virome at single-nucleotide resolution. [PDF]

Microbiome
Large-scale characterization of gut viral genomes provides strain-resolved insights into host-microbe interactions. However, existing viral genomes are mainly derived from Western populations, limiting our understanding of global gut viral diversity and ...
Wang X, Dong Q, Huang P, Yang S, Gao M, Zhang C, Zhang C, Deng Y, Huang Z, Ma B, Jiao Y, Zhou Y, Wu T, Zou H, Shi J, Sheng Y, Wang Y, Consortium C, Tang L, Hu S, Duan Y, Sun W, Chen W, Zhai Q, Kong X, Chen L.   +25 more
europepmc   +3 more sources

The Gut Virome Database Reveals Age-Dependent Patterns of Virome Diversity in the Human Gut [PDF]

Cell Host & Microbe, 2020
The gut microbiome profoundly affects human health and disease, and their infecting viruses are likely as important, but often missed because of reference database limitations.
Ann C. Gregory, Olivier Zablocki, A. Zayed, Allison Howell, B. Bolduc, M. Sullivan   +5 more
semanticscholar   +3 more sources

A signature-protein-based approach for accurate and efficient profiling of the human gut virome. [PDF]

Cell Rep Methods
Summary The human gut virome represents a critical yet underexplored component that regulates bacterial communities and maintains gut health. However, virome analysis remains challenging due to the vast diversity and genomic variability.
Yang F, Xiong L, Li M, Feng X, Ren H, Shi Z, Zhong H, Li J.   +7 more
europepmc   +2 more sources