Results 61 to 70 of about 78,351 (172)

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

Metagenomic Analyses of Multiple Gut Datasets Revealed the Association of Phage Signatures in Colorectal Cancer

Frontiers in Cellular and Infection Microbiology, 2022
The association of colorectal cancer (CRC) and the human gut microbiome dysbiosis has been the focus of several studies in the past. Many bacterial taxa have been shown to have differential abundance among CRC patients compared to healthy controls ...
Wenxuan Zuo, Sonia Michail, Fengzhu Sun
doaj   +1 more source

Therapeutic Potential of Fecal Microbiota Transplantation for Male Sexual Dysfunction: Evidence and Clinical Perspectives

Microbiota Medicine Research, EarlyView.
ABSTRACT Fecal microbiota transplantation (FMT), a microbiome‐based therapy, shows potential in treating male sexual dysfunction. Research into the influence of FMT on male sexual function has recently garnered increasing attention. This review aims to explore the impact of FMT on male sexual function and the underlying mechanisms, and to analyze the ...
Junyi Chen, Chenfeng Bu, Xia Li, Lei Wu, Xingxiang He   +4 more
wiley   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Gut virome and its implications in the pathogenesis and therapeutics of inflammatory bowel disease

BMC Medicine
Inflammatory bowel disease (IBD) refers to chronic, recurrent inflammatory intestinal disorders, primarily including Crohn’s disease (CD) and Ulcerative colitis (UC). Numerous studies have elucidated the importance of the gut microbiome in IBD. Recently,
Yushan Wu, Rui Cheng, Hao Lin, Lili Li, Yongbin Jia, Anna Philips, Tao Zuo, Hu Zhang   +7 more
doaj   +1 more source

The human gut virome: Composition, colonisation, interactions, and impacts on human health

, 2022
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in many disease 9 states, but it is not yet known to what extent the gut virome impacts everyday human health. New 10 experimental and bioinformatic approaches are required to address this knowledge gap.
Evan Pargin, Michael Roach, Amber Skye, Robert Edwards, Sarah Giles   +4 more
openaire   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Activity‐Informed Network Analysis Reveals Keystone Microbes Shaping Freshwater Ecosystem Function

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Graphical abstract illustrating the workflow and key findings of this study. We first applied SPIEC‐EASI to metagenomic abundance data to construct microbial co‐occurrence networks and selected the top 15 MAGs based on degree centrality. We then used CARlasso to detect relationships between the top MAGs and environmental features.
Qiyao Yang, Rosa Aghdam, Patricia Q. Tran, Karthik Anantharaman, Claudia Solís‐Lemus   +4 more
wiley   +1 more source

Viral metagenomics reveals diverse viruses in the fecal samples of children with acute respiratory infection

Frontiers in Microbiology
IntroductionChanges in the gut microbiome have been associated with the development of acute respiratory infection (ARI). However, due to methodological limitations, our knowledge of the gut virome in patients with ARIs remains limited.MethodsIn this ...
Pan Xu, Chunduo Pan, Minli Yuan, Ying Zhu, Shanjie Wei, Hongyan Lu, Wen Zhang   +6 more
doaj   +1 more source

Safeguarding a Flagship Species: Integrated Surveillance of Cross‐Species Pathogen Transmission in Giant Panda Ecosystems

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun, Yi Peng, Xiaoye Hao, Rong Dong, Zhilin Wang, Le Wang, Chengdong Wang, Xiangdong Wu, Zheng Chen, Wenbo Zhang, Xiaoli Tang   +10 more
wiley   +1 more source