Results 51 to 60 of about 8,128 (169)

Metagenomic Analyses of Multiple Gut Datasets Revealed the Association of Phage Signatures in Colorectal Cancer

Frontiers in Cellular and Infection Microbiology, 2022
The association of colorectal cancer (CRC) and the human gut microbiome dysbiosis has been the focus of several studies in the past. Many bacterial taxa have been shown to have differential abundance among CRC patients compared to healthy controls ...
Wenxuan Zuo, Sonia Michail, Fengzhu Sun
doaj   +1 more source

Characterization of virus-like particles associated with the human faecal and caecal microbiota [PDF]

, 2014
This work represents an investigation into the presence, abundance and diversity of virus-like particles (VLPs) associated with human faecal and caecal samples.
Anne L. McCartney, Breitbart, Breitbart, Brüssow, Colombet, Colson, Douwe van Sinderen, Edwards, Fuhrman, Glenn R. Gibson, Horst Neve, Hoyles, Hoyles, Hoyles, Jeremy D. Sanderson, Jones, Klieve, Knut J. Heller, Kulikov, Lepage, Lesley Hoyles, Meader, Mills, Minot, Minot, Modi, Patel, Reyes, Rohozinski, Rohwer, Sime-Ngando, Thurber, Vishwakarma, Wagner, Watanabe, Wen, Zhang   +36 more
core   +2 more sources

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Human oral viruses are personal, persistent and gender-consistent. [PDF]

, 2014
Viruses are the most abundant members of the human oral microbiome, yet relatively little is known about their biodiversity in humans. To improve our understanding of the DNA viruses that inhabit the human oral cavity, we examined saliva from a cohort of
A Gomez, A Kovacs, A Reyes, AD Weinberger, AJ Saldanha, Andrew G Lum, AS Whiteley, B Rodriguez-Brito, BA Duerkop, C Desnues, C Lay, C Lozupone, D Willner, D Willner, David T Pride, DT Pride, DT Pride, DT Pride, EJ Summer, F Rodriguez-Valera, FA Murphy, FE Dewhirst, H Loe, HA Schenkein, HK Allen, Human Microbiome Project Consortium, IT Paulsen, J Slots, JG Caporaso, JG Caporaso, JG Markle, JM Rothberg, JR Cole, Julia Salzman, KE Wommack, KH Kim, M Breitbart, M Breitbart, M Craven, M Li, M Umeda, M Yoshida, Melissa Ly, MN Price, N Fierer, PJ Turnbaugh, PP Sedghizadeh, PS Kumar, Q Wang, Q Zhang, R Barrangou, R Cooksey, R Robles-Sikisaka, RA Sandaa, RC Edgar, RE Ley, RE Ley, Refugio Robles-Sikisaka, S Huang, S Minot, S Minot, S Mueller, S Roux, Shira R Abeles, T Staudinger, TG Phan, Tobias K Boehm, TZ DeSantis, V Parada, W Li, WG Wade, X Ge   +71 more
core   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Gut virome and its implications in the pathogenesis and therapeutics of inflammatory bowel disease

BMC Medicine
Inflammatory bowel disease (IBD) refers to chronic, recurrent inflammatory intestinal disorders, primarily including Crohn’s disease (CD) and Ulcerative colitis (UC). Numerous studies have elucidated the importance of the gut microbiome in IBD. Recently,
Yushan Wu, Rui Cheng, Hao Lin, Lili Li, Yongbin Jia, Anna Philips, Tao Zuo, Hu Zhang   +7 more
doaj   +1 more source

Microbial diversity in individuals and their household contacts following typical antibiotic courses. [PDF]

, 2016
BackgroundAntibiotics are a mainstay of treatment for bacterial infections worldwide, yet the effects of typical antibiotic prescriptions on human indigenous microbiota have not been thoroughly evaluated.
Abeles, Shira R, Jones, Marcus B, Klitgord, Niels, Ly, Melissa, Nelson, Karen E, Pride, David T, Santiago-Rodriguez, Tasha M, Yooseph, Shibu   +7 more
core   +2 more sources

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Viral metagenomics reveals diverse viruses in the fecal samples of children with acute respiratory infection

Frontiers in Microbiology
IntroductionChanges in the gut microbiome have been associated with the development of acute respiratory infection (ARI). However, due to methodological limitations, our knowledge of the gut virome in patients with ARIs remains limited.MethodsIn this ...
Pan Xu, Chunduo Pan, Minli Yuan, Ying Zhu, Shanjie Wei, Hongyan Lu, Wen Zhang   +6 more
doaj   +1 more source

Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung, Eirini Militsi, Olivier Huck   +2 more
wiley   +1 more source