Results 121 to 130 of about 27,320,927 (309)

Quantitative fully integrated life cycle assessment (LCA) with Human Health Risk Assessment (HHRA): deliverable 7.4

This deliverable describes the work carried out within Task 7.4 of WP7 of the PeroCUBE project. Task 7.4 aims at performing the life cycle assessment (LCA) of three PeroCUBE devices integrated with a Human Health Risk Assessment (HHRA).
Fransman, W., Shandilya, N., Ligthart, T., Simon, L. de   +3 more
core  

Connecting diversity and process: Eukaryotic phytoplankton community dynamics across the Yangtze River using environmental DNA

Ecological Indicators
Rivers are collectors of both water and environmental changes in a catchment area, and act as dispersal pathways for biodiversity. But it remains unclear whether, and how strongly, environmental changes and dispersal dynamics shape the phytoplankton ...
Yun Shao, Kathryn A. Stewart, Alena S. Gsell, Shuping Wang, Boyuan Xie, Haojie Lin, Zhaomei Geng, Zhenguang Yan   +7 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Other title: Health Risk Behaviors of Kansas, 2012 Behavioral Risk Factor Surveillance System, 2012

, 2014
March 2014Behavioral Risk Factor Surveillance System Overview -- Leading Health Indicators -- Physical Activity -- Obesity -- Tobacco Use -- Substance Abuse -- Injury and Violence -- Immunizations -- Access to Health Care -- Featured Issues in 2003 ...
Kansas. Office of Health Promotion; Kansas. Department of Health and Environment
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Analyzing the Relationship between Objective-Subjective Health Status and Public Perception of Climate Change as a Human Health Risk in Coastal Tanzania

, 2015
Climate change is considered as the biggest threat to human health in the 21st century. Sub-Saharan Africa, which is the most-at-risk region of the world, is estimated to have a disproportionately large share of the burden of climate change-induced ...
Chuenpagdee, Ratana, Hambati, Herbert, Campbell, Gwyn, Armah, Frederick Ato, Tambang, Yengoh Genesis, Luginaah, Isaac, Tambang, Yengoh Genesis,, Lund University.   +7 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Ecological and Health Risk Assessment of Metals in Organic and Conventional Peruvian Coffee from a Probabilistic Approach

Agronomy
This study aims to understand the risks posed by metals in Peruvian coffee plantations to human health and environmental integrity, ensuring the protection of local communities and the ecosystems reliant on this agricultural activity.
Grobert A. Guadalupe, Ligia García, Segundo G. Chavez, Eva Doménech   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source