Results 1 to 10 of about 1,991,588 (267)
Characterization of Arabian Peninsula whole exomes: Contributing to the catalogue of human diversity
iScience, 2022 Summary: The cataloging of human genomic variation is a challenging task given the size and diversity of the global human population. Several geographic regions remain under-characterized, such as the Arabian Peninsula (AP), which is unique in being at ...
Joana C. Ferreira +3 more
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iScience, 2022 Summary: Slow oxidative muscle, most notably the soleus, is inherently well equipped with the molecular machinery for regulating blood-borne substrates.
Marc T. Hamilton +2 more
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MAP3K19 regulatory variation in populations with African ancestry may increase COVID-19 severity
iScience, 2023 Summary: To identify ancestry-linked genetic risk variants associated with COVID-19 hospitalization, we performed an integrative analysis of two genome-wide association studies and resolved four single nucleotide polymorphisms more frequent in COVID-19 ...
Zhongshan Cheng +7 more
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Estimated 24-h urinary sodium excretion and risk of end-stage kidney disease
iScience, 2023 Summary: The association between sodium intake and long-term kidney disease endpoints is debated and yet to be proven. We aimed to investigate the associations of estimated 24-h urinary sodium excretion, reflecting daily sodium intake, with the incidence
Ying Shan +11 more
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Environmental Exposure Science and Human Health
International Journal of Environmental Research and Public Health, 2023 Human health and environmental exposure form an inseparable binomial [...]
Anna M. Lavezzi, Bruno Ramos-Molina
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Overcoming cohort heterogeneity for the prediction of subclinical cardiovascular disease risk
iScience, 2023 Summary: Cardiovascular disease remains a leading cause of mortality with an estimated half a billion people affected in 2019. However, detecting signals between specific pathophysiology and coronary plaque phenotypes using complex multi-omic discovery ...
Adam S. Chan +7 more
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The Genetic contribution to solving the cocktail-party problem
iScience, 2022 Summary: Communicating in everyday situations requires solving the cocktail-party problem, or segregating the acoustic mixture into its constituent sounds and attending to those of most interest.
Samuel R. Mathias +15 more
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iScience, 2023 Summary: Body-mass index (BMI) is a hallmark of adiposity. In contrast with adulthood, the genetic architecture of BMI during childhood is poorly understood.
Lucas Vicuña +10 more
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Endogenous Metabolic Modulators: Emerging Therapeutic Potential of Amino Acids
iScience, 2020 Summary: Multifactorial disease pathophysiology is complex and incompletely addressed by existing targeted pharmacotherapies. Amino acids (AAs) and related metabolites and precursors are a class of endogenous metabolic modulators (EMMs) that have diverse
Michael J. Hamill +3 more
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Science, health, and human rights
Global Public Health, 2021 A solid knowledge base is one of the necessary conditions to assure health as a human right. The contemporary source of such knowledge are the sciences at large, which however presents a problem, since the scientific enterprise can - and has been - a source of human rights violations as well.
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