Results 21 to 30 of about 30,135,302 (286)

Cord serum metabolic signatures of future progression to immune-mediated diseases

iScience, 2023
Summary: Previous prospective studies suggest that progression to autoimmune diseases is preceded by metabolic dysregulation, but it is not clear which metabolic changes are disease-specific and which are common across multiple immune-mediated diseases ...
Tuulia Hyötyläinen, Bagavathy Shanmugam Karthikeyan, Tannaz Ghaffarzadegan, Eric W. Triplett, Matej Orešič, Johnny Ludvigsson   +5 more
doaj   +1 more source

A Genetic modification that reduces ON-bipolar cells in hESC-derived retinas enhances functional integration after transplantation

iScience, 2022
Summary: Pluripotent stem cell (PSC)-derived retinal sheet transplanted in vivo can form structured photoreceptor layers, contact with host bipolar cells, and transmit light signals to host retinas.
Suguru Yamasaki, Hung-Ya Tu, Take Matsuyama, Matsuri Horiuchi, Tomoyo Hashiguchi, Junki Sho, Atsushi Kuwahara, Akiyoshi Kishino, Toru Kimura, Masayo Takahashi, Michiko Mandai   +10 more
doaj   +1 more source

Probiotic Limosilactobacillus fermentum GR-3 ameliorates human hyperuricemia via degrading and promoting excretion of uric acid

iScience, 2022
Summary: Probiotics have demonstrated the potential to ameliorate hyperuricemia in animals, but their effectiveness and mechanism of action in humans has been understudied.
Shuai Zhao, Pengya Feng, Xiaogang Hu, Wenjuan Cao, Pu Liu, Huawen Han, Weilin Jin, Xiangkai Li   +7 more
doaj   +1 more source

Training effects of set- and repetition-interval rest time on recumbent-boxing exercise: Could virtual reality improve further?

iScience, 2023
Summary: This study examined the influence of set-interval and repetition-interval rest time of virtual reality (VR) boxing game in supine-lying posture.
Yi Wang, Qi Chen, Liangchao Liu, Qiuhong He, James Chung-Wai Cheung, Duo Wai-Chi Wong, Yang Liu, Wing-Kai Lam   +7 more
doaj   +1 more source

Protein supplementation changes gut microbial diversity and derived metabolites in subjects with type 2 diabetes

iScience, 2023
Summary: High-protein diets are promoted for individuals with type 2 diabetes (T2D). However, effects of dietary protein interventions on (gut-derived) metabolites in T2D remains understudied. We therefore performed a multi-center, randomized-controlled,
Ilias Attaye, Pierre Bel Lassen, Solia Adriouch, Emilie Steinbach, Rafael Patiño-Navarrete, Mark Davids, Rohia Alili, Flavien Jacques, Sara Benzeguir, Eugeni Belda, Ina Nemet, James T. Anderson, Laure Alexandre-Heymann, Arno Greyling, Etienne Larger, Stanley L. Hazen, Sophie L. van Oppenraaij, Valentina Tremaroli, Katharina Beck, Per-Olof Bergh, Fredrik Bäckhed, Suzan P.M. ten Brincke, Hilde Herrema, Albert K. Groen, Sara-Joan Pinto-Sietsma, Karine Clément, Max Nieuwdorp   +26 more
doaj   +1 more source

Single high-fat challenge and trained innate immunity: A randomized controlled cross-over trial

iScience
Summary: Brief exposure of monocytes to atherogenic molecules, such as oxidized lipoproteins, triggers a persistent pro-inflammatory phenotype, named trained immunity.
Julia van Tuijl, Julia I.P. van Heck, Harsh Bahrar, Wieteke Broeders, Johan Wijma, Yvonne M. ten Have, Martin Giera, Heidi Zweers-van Essen, Laura Rodwell, Leo A.B. Joosten, Mihai G. Netea, Lydia A. Afman, Siroon Bekkering, Niels P. Riksen   +13 more
doaj   +1 more source

Time-restricted eating improves health because of energy deficit and circadian rhythm: A systematic review and meta-analysis

iScience
Summary: Time-restricted eating (TRE) is an effective way to lose weight and improve metabolic health in animals. Yet whether and how these benefits apply to humans is unclear. This systematic review and meta-analysis examined the effect of TRE in people
Yuwen Chang, Tingting Du, Xiangling Zhuang, Guojie Ma   +3 more
doaj   +1 more source

The Precautionary Principle, Science and Human Health Protection

Human and Ecological Risk Assessment: An International Journal, 2005
As technology advances rapidly, so do applications with potential adverse implications on human health. The possible threats include risks that can be substantial, far-reaching and irreversible, and currently available methods of investigation, designed to deal with direct exposure-disease associations, are not always suitable.
Marco, Martuzzi, Roberto, Bertollini
openaire   +2 more sources

School of Health & Applied Human Sciences health matters

, 2015
A newsletter to inform the community about Health and Applied Human Sciences, a school within the College of Health and Human ...
University of North Carolina, Wilmington. College of Health and Human Services
core   +2 more sources

The effect of Working Alliance on drug attitude in patients with Major Depressive Disorder

European Psychiatry, 2022
Introduction Working Alliance is defined as the emotional bond and the agreement on therapeutic goals and tasks between patients and therapists. Despite the wide use of the construct of working alliance in research on psychotherapy, few studies have ...
G. Santarelli, G. Sanfilippo, F. Benvenuti, L. Santoro, A. Nistri, M. Innocenti, A. Ballerini, V. Ricca   +7 more
doaj   +1 more source