Results 101 to 110 of about 6,269,925 (357)

Effects of air pollution on human health and practical measures for prevention in Iran

Journal of Research in Medical Sciences, 2016
Air pollution is a major concern of new civilized world, which has a serious toxicological impact on human health and the environment. It has a number of different emission sources, but motor vehicles and industrial processes contribute the major part of
A. Ghorani-Azam, B. Riahi-Zanjani, M. Balali-Mood   +2 more
semanticscholar   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Proceedings of the CIDESD International Congress 2025

Motricidade
The papers published in these proceedings were submitted to the Scientific Committee of the CIDESD International Congress 2025, held from June 5 to 7, at Covilhã, Portugal. Authors are exclusively responsible for the content of the manuscript published.
Daniel Almeida Marinho, João Viana, Paula Mota   +2 more
doaj   +1 more source

Opportunities to integrate new approaches in genetic toxicology: An ILSI-HESI workshop report [PDF]

, 2014
Genetic toxicity tests currently used to identify and characterize potential human mutagens and carcinogens rely on measurements of primary DNA damage, gene mutation, and chromosome damage in vitro and in rodents.
Aardema, Marilyn J., Auerbach, Scott, Boverhof, Darrell, Custer, Laura, Dedon, Peter C., Gollapudi, Bhaskar, Honma, Masamitsu, Ishida, Seiichi, Kasinski, Andrea L., Kim, James H., Manjanatha, Mugimane G., Marlowe, Jennifer, Pfuhler, Stefan, Pogribny, Igor, Slikker, William, Stankowski, Leon F., Tanir, Jennifer Y., Thybaud, Véronique, Tice, Raymond, van Benthem, Jan, White, Paul, Witt, Kristine L., Zeiger, Errol   +22 more
core   +1 more source

Lignins and Their Derivatives with Beneficial Effects on Human Health

International Journal of Molecular Sciences, 2017
A review of the pharmacological applications of lignins provides evidence of their protective role against the development of different diseases. In many cases, the effects of lignins could be explained by their antioxidant capacity.
M. Vinardell, M. Mitjans
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Prevalence and impact of diabetes in patients with valvular heart disease

iScience
Summary: This study aimed to investigate the prevalence of diabetes in valvular heart disease (VHD), as well as the relationship of diabetes with severity of valvular lesions and clinical outcome.
Qianhong Lu, Junxing Lv, Yunqing Ye, Zhe Li, Weiwei Wang, Bin Zhang, Qinghao Zhao, Zhenyan Zhao, Haitong Zhang, Qingrong Liu, Bincheng Wang, Zikai Yu, Shuai Guo, Zhenya Duan, Yanyan Zhao, Runlin Gao, Haiyan Xu, Yongjian Wu   +17 more
doaj   +1 more source

Evolving geographic diversity in SARS-CoV2 and in silico analysis of replicating enzyme 3CLpro targeting repurposed drug candidates

Journal of Translational Medicine, 2020
Background Severe acute respiratory syndrome (SARS) has been initiating pandemics since the beginning of the century. In December 2019, the world was hit again by a devastating SARS episode that has so far infected almost four million individuals ...
Nitin Chitranshi, Vivek K. Gupta, Rashi Rajput, Angela Godinez, Kanishka Pushpitha, Ting Shen, Mehdi Mirzaei, Yuyi You, Devaraj Basavarajappa, Veer Gupta, Stuart L. Graham   +10 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source