Results 31 to 40 of about 6,269,925 (357)

Cord serum metabolic signatures of future progression to immune-mediated diseases

iScience, 2023
Summary: Previous prospective studies suggest that progression to autoimmune diseases is preceded by metabolic dysregulation, but it is not clear which metabolic changes are disease-specific and which are common across multiple immune-mediated diseases ...
Tuulia Hyötyläinen, Bagavathy Shanmugam Karthikeyan, Tannaz Ghaffarzadegan, Eric W. Triplett, Matej Orešič, Johnny Ludvigsson   +5 more
doaj   +1 more source

Neutrosophy and Health Sciences: a necessary alliance

Revista Información Científica, 2023
Health is the truth of life, it is a fundamental quality of the human being that is expressed in each of its four dimensions (biological, ecological, social and spiritual) and defines human nature.
Alfredo Pardo-Fernández, Yamilé Rodríguez-Sotomayor   +1 more
doaj   +1 more source

Riboflavin Deficiency—Implications for General Human Health and Inborn Errors of Metabolism

International Journal of Molecular Sciences, 2020
As an essential vitamin, the role of riboflavin in human diet and health is increasingly being highlighted. Insufficient dietary intake of riboflavin is often reported in nutritional surveys and population studies, even in non-developing countries with ...
S. Mosegaard, G. Dipace, P. Bross, J. Carlsen, N. Gregersen, R. Olsen   +5 more
semanticscholar   +1 more source

Protein supplementation changes gut microbial diversity and derived metabolites in subjects with type 2 diabetes

iScience, 2023
Summary: High-protein diets are promoted for individuals with type 2 diabetes (T2D). However, effects of dietary protein interventions on (gut-derived) metabolites in T2D remains understudied. We therefore performed a multi-center, randomized-controlled,
Ilias Attaye, Pierre Bel Lassen, Solia Adriouch, Emilie Steinbach, Rafael Patiño-Navarrete, Mark Davids, Rohia Alili, Flavien Jacques, Sara Benzeguir, Eugeni Belda, Ina Nemet, James T. Anderson, Laure Alexandre-Heymann, Arno Greyling, Etienne Larger, Stanley L. Hazen, Sophie L. van Oppenraaij, Valentina Tremaroli, Katharina Beck, Per-Olof Bergh, Fredrik Bäckhed, Suzan P.M. ten Brincke, Hilde Herrema, Albert K. Groen, Sara-Joan Pinto-Sietsma, Karine Clément, Max Nieuwdorp   +26 more
doaj   +1 more source

Mechanomorphosis: Science, Management, and “Human Machinery” in Industrial Canada, 1900–45 [PDF]

, 1998
By the early 20th century, the changes taking place in western industrial capitalist nations prompted an adaptive shift in the socioeconomic delineation of human bodies, and in scientific theories about how they worked and how they could be put to work ...
Comacchio, Cynthia
core   +2 more sources

Molecular Aspects of Mycotoxins—A Serious Problem for Human Health

International Journal of Molecular Sciences, 2020
Mycotoxins are toxic fungal secondary metabolities formed by a variety of fungi (moulds) species. Hundreds of potentially toxic mycotoxins have been already identified and are considered a serious problem in agriculture, animal husbandry, and public ...
Edyta Janik, M. Niemcewicz, Michal Ceremuga, Maksymilian Stela, Joanna Saluk-Bijak, Adrian Siadkowski, M. Bijak   +6 more
semanticscholar   +1 more source

A Genetic modification that reduces ON-bipolar cells in hESC-derived retinas enhances functional integration after transplantation

iScience, 2022
Summary: Pluripotent stem cell (PSC)-derived retinal sheet transplanted in vivo can form structured photoreceptor layers, contact with host bipolar cells, and transmit light signals to host retinas.
Suguru Yamasaki, Hung-Ya Tu, Take Matsuyama, Matsuri Horiuchi, Tomoyo Hashiguchi, Junki Sho, Atsushi Kuwahara, Akiyoshi Kishino, Toru Kimura, Masayo Takahashi, Michiko Mandai   +10 more
doaj   +1 more source

Probiotic Limosilactobacillus fermentum GR-3 ameliorates human hyperuricemia via degrading and promoting excretion of uric acid

iScience, 2022
Summary: Probiotics have demonstrated the potential to ameliorate hyperuricemia in animals, but their effectiveness and mechanism of action in humans has been understudied.
Shuai Zhao, Pengya Feng, Xiaogang Hu, Wenjuan Cao, Pu Liu, Huawen Han, Weilin Jin, Xiangkai Li   +7 more
doaj   +1 more source

Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions. [PDF]

, 2019
On December 17, 2018, the North American branch of the International Life Sciences Institute (ILSI North America) convened a workshop "Can We Begin to Define a Healthy Gut Microbiome Through Quantifiable Characteristics?" with >40 invited academic ...
Antonopoulos, Armitage, AVA, Singapore, Azad, Backhed, Barbara O Schneeman, Beaton, Beukers, Bindels, Bindels, Borewicz, Brazilian Health Regulatory Agency (ANVISA), Buddington, Cammarota, Campbell-Lendrum, Cantarel, Caporaso, Carlson, Cindy Davis, Claire M Fraser, Costea, Cummings, Curtis Huttenhower, Damen, Dao, David, David, Davis, Davoren, Desai, Deschasaux, Dethlefsen, De Preter, Earle, EFSA, EFSA, Eloe-Fadrosh, Esaiassen, European Commission, European Commission, Falony, FAO and WHO, FAO and WHO, FDA, FDA, FDA, FDA, FDA, FDA, FDA, FDA, FDA-NIH Biomarker Working Group, Fedacko, Fei, Ferretti, Fischbach, Flaherman, Flint, Forbes, Foster, Fragiadakis, Francois, François, François, Gibson, Government of Canada, Gregory, Gupta, Hadizadeh, He, Health Canada, Health Canada, Health Canada, Health Canada, Health Canada, Health Canada, Hermansson, Hildebrand, Ho, Holmes, Holmes, Holscher, Insel, Jacobsen, Jakobsson, Jangi, Janssens, Japan Consumer Affairs Agency, Japan Consumer Affairs Agency, Japan Ministry of Health, Labour, and Welfare, Japan Ministry of Health, Labour, and Welfare, Jens Walter, Jones, Kennedy, Koenig, Korpela, Kristensen, Kristin Verbeke, Kritchevsky, Krumbeck, Lahti, Lam, Langdon, Lawley, La Fata, Leiby, Lim, Lloyd-Price, Lohner, Lozupone, Makki, Maldonado-Gómez, Marcobal, Marie E Latulippe, Martin, Martinez, Martínez, Martínez, Martínez, Matamoros, McBurney, McBurney, McBurney, McFarland, Michael I McBurney, Miller, MOH Malaysia, MOH Malaysia, MOPH Thailand, Mould, Mueller, NDAC, Palleja, Perez-Muñoz, Rattanaprasert, Roager, Robb, Rothschild, Round, Russell, Rutishauser, Saxelin, Schloissnig, Schlomann, Schneeberger, Schroeder, Snijder, Song, Sonnenburg, Sonnenburg, Sprockett, Sundin, Surana, Tanemura, Tannock, Taverniti, The Human Microbiome Project Consortium, Tremlett, Trowell, Vandeputte, Vangay, Vatanen, Vellend, Venkataraman, Venkataraman, Voigt, von Wintzingerode, Walter, Wan, Wang, Watson, Wedekind, Windey, Windey, Windey, Wong, Wu, Yassour   +177 more
core   +2 more sources

An evaluation framework for new approach methodologies (NAMs) for human health safety assessment.

Regulatory toxicology and pharmacology : RTP, 2020
The need to develop new tools and increase capacity to test pharmaceuticals and other chemicals for potential adverse impacts on human health and the environment is an active area of development.
Stanley T. Parish, M. Aschner, W. Casey, M. Corvaro, M. Embry, S. Fitzpatrick, D. Kidd, N. Kleinstreuer, B. Lima, R. Settivari, D. Wolf, D. Yamazaki, A. Boobis   +12 more
semanticscholar   +1 more source