Results 91 to 100 of about 786,922 (346)
Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]
, 2018 The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.Chen, Yuan-Chuan, Liu, Fenyong, Sheng, Jingxue, Trang, Phong +3 morecore +5 more sourcesHSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]
, 2001 Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...Arbusow, Viktor, Brandt, Thomas, Mascolo, Andrea, Strupp, Michael, Theil, Diethilde +4 morecore +1 more sourceEfficacy and Safety of Subcutaneous Efgartigimod PH20 in Adults With Primary Immune Thrombocytopenia (ADVANCE SC): A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled, Phase 3 Trial
American Journal of Hematology, EarlyView.ABSTRACT
Primary autoimmune thrombocytopenia (ITP) is characterized by thrombocytopenia, bleeding, and reduced health‐related quality of life. In the Phase 3 ADVANCE IV study, intravenous efgartigimod induced significant platelet count responses versus placebo in patients with chronic ITP. ADVANCE SC, a Phase 3, multicenter, randomized, double‐blinded, Nichola Cooper, Catherine M. Broome, Yoshitaka Miyakawa, Vickie McDonald, Hanny Al‐Samkari, Abderrahim Khelif, Spero R. Cataland, Wilma Barcellini, Renchi Yang, Heng Mei, Filip Matthijssens, Anna Hultberg, Giorgia Ciurlia, Domenica Gandini, Jaume Ayguasanosa, Kristof De Beuf, Ségolène Pastouret, Waleed Ghanima, Francesco Rodeghiero, James B. Bussel, the ADVANCE SC Investigator Trial Group, Marcela Sarmiento, Anahi Rollheiser, Hugo Ferro, Victoria Caula, Edgardo Garcia Espina, Sebastian Pastoriza, Ross I Baker, Maan Alwan, Peter Thian Guan Tan, Jir‐Ping Boey, Jack Karel Driml, Jennifer Curnow, Emily Blyth, Taryn Freeman, Amanda Johnston, John Kwan, Chun Ma, Jonathan Marwick, Kenneth Micklethwaite, Lachlin Vaughan, Zane Kaplan, Gareth Gregory, Emma Leitinger, Christopher Leow, Alexandra Murton, Jeremy Ong, Ross Salvaris, Maciej Jan Tatarczuch, Jonathan Wong, Ahmad Zargari, Michael Leahy, Philip Young‐Ill Choi, Angeline Audrey Achola Josiah, Kisoth Arasaratnam, Fathima Ayyalil, Samuel Bennett, Philip Crispin, James D’Rozario, Melanie D’Souza, Thomas Gleeson, Maya Latimer, Edwin Lee, Jun Lim, Ross Lindell‐Innes, Mridula Mokoonlall, Jun Ng, Nalini Pati, Michael Pidcock, Kristy Natasha Rady, Caitllin Thirunavukarasu, Pencho Georgiev, Maria Dimitrova, Zhanet Grudeva‐Popova, Bulent Nihat, Alexander M. Arellano Rojas, Christine M. Rojas Hopkins, Eugenia Loredo Fort, Eduardo P. Yáñez Ruiz, Mauro Leandro Morales Sanhueza, Patricio Yanez Weber, Renchi Yang, Yunfei Chen, Ting Sun, Yun Zhuang, Lei Yang, Feng Zhang, Jiajia Li, Jun Li, Lin Liu, Meng Wang, Yanli Yang, Fangbing Zhu, Junfeng Zhu, Heng Mei, Danying Liao, Quizhe Wei, Hu Zhou, Bingjie Ding, Mengjuan Li, Xuewen Song, Lina Zhang, Yuanyuan Zhang, Liang Wang, Jia Cong, Liqiang Wei, Na Yao, Hongyu Zhang, Silang Chen, Jia Feng, Lihua Sun, Haichan Xu, Lei Xu, Qian Zhang, Fengluan Zhong, Guo wei Li, Guoshu Chen, Li Chen, Xiaoyu Chen, Dongting Liu, Xiaohua Qin, Xiaoling Xie, Xiaoming Fei, D. Wenping Lu, Yilong Lu, Ming Luo, Lixia Wang, Xianqiu Yu, Xin Wang, Chao Ding, Xiaoqiong Duan, Wenhua He, Liping Huan, Yanqiu Li, Juan Liu, Ningning Tang, Wei Yin, Mamia Zodelva, Irine Datikashvili‐David, Nino Sharashenidze, Levan Makhaldiani, Teano Gamezardashvili, Ekaterine Gaprindashvili, Tamar Gersamia, Magdana Betaneli, Tamta Makharadze, Anargyros Symeonidis, Maria‐Lamprini Kasti, Alexandra Kourakli, Vasileios Lazaris, Andi Prekazi, Angelos Sarantopoulos, Marina Mantzourani, Vasiliki Antoniadou, Dimitra Vlachopoulou, Antonia Syrigou, Achilles Anagnostopoulos, Eleni Gavriilaki, Michail Iskas, Ioanna Sakellari, Christos Varelas, Ronan G. Desmond, Paraic Behan, Helen Enright, Christopher Fox, John McHugh, Grace Rothwell‐Kelly, Louisa Shackleton, Ilana Levy‐Yurkovski, Natalia Kreiniz, Sarah Matarasso‐Greenfeld, Tamar Tadmor, Anatoly Nemets, Alexander Avroutine, Yosef Barshay, Tatiana Boulygin, Shirley Zafrir‐Haver, Andrea Patriarca, Riccardo Moia, Maura Nocolosi, Wilma Barcellini, Bruno Fattizzo, Juri Giannotta, Felicetto Ferrara, Barbara Pocali, Antonio Cuneo, Maurizio Cavallari, Francesco Cavazzini, Maria Ciccone, Gian Matteo, Mariarosaria Sessa, Paolo Tomasi, Antonio Urso, Fabrizio Pane, Federico Chiurazzi, Giada Muccioli Casadei, Alessandro Lucchesi, Maria Giannini, Giovanni Marconi, Giorgia Micucci, Marianna Norata, Monica Poggiaspalla, Elena Rossi, Valerio De Stefano, Tomoki Ito, Shinya Fujita, Masaaki Hotta, Akiko Konishi, Takahisa Nakanishi, Atsushi Satake, Hideaki Yoshimura, Akio Saito, Naoki Akashi, Hirono Iriuchishima, Akira Matsumoto, Morio Matsumoto, Masahiro Mihara, Keita Nakayama, Morio Sawamura, Yukie Terasaki, Yoshitaka Miyakawa, Ryohei Abe, Atsushi Ohsaki, Kohei Saito, Rie Shiomi, Kodai Suzuki, Kento Umino, Shoko Ito, Masahiro Ashiwaza, Shinichiro Fujiwara, Kaoru Morita, Yoshinobu Kanda, Daisuke Minakata, Rui Murahashi, Hirotomo Nakashima, Ken Ohmine, Tsukasa Ohmori, Kazuya Sato, Yumiko Toda, Masuzu Ueda, Chihiro Yamamoto, Katsutoshi Ozaki, Yuya Kishida, Yasuko Kuribayashi, Keita Kirito, Eriko Hosokawa, Hideto Hyuga, Ichiro Kawashima, Megumi Koshiishi, Takuma Kumagai, Minori Matsuura, Kei Nakajima, Yuma Sakamotot, Masaru Tanaka, Takeo Yamamoto, Ryosuke Ogawa, Kenichi Aoki, Kentaro Kohno, Akihiko Numata, Teppei Obara, Yotaro Tamai, Wataru Kamata, Teiko Kawahigashi, Shuku Sato, Shun Tsunado, Shigeki Ito, Shugo Kowata, Tatsuo Oyake, Suleimman Al‐Sweedan, Dalia Alsweedan, Raghad Irshaid, Nour Sameeh, Muath Thiabat, Abdalla Awidi Abbadi, Feras Al Fararjeh, Alaa Alshorman, Jong‐Ho Won, Kyoung Ha Kim, Seug Yun Yoon, Soo‐Mee Bang, Sang‐A Kim, Jeong‐Ok Lee, Ji Yun Lee, June‐Won Cheong, Ji Eun Jang, Hyun Soo Cho, Haerim Chung, Doh Yu Hwang, Yu Ri Kim, Hyewon Kook, Yunsuk Choi, Kyoo‐Hyung Lee, Eun‐Ji Choi, Je‐Hwan Lee, Jung‐Hee Lee, Hang‐Seung Park, Mariela Cardiel Silva, Ivan Gamez Valdez, Karen Miranda Fernandez, Carlos Chavez Trillo, Alva Zaragoza Vazquez, Marco A. Velasco Rojas, Ximena Arenas Reyes, Jessica Graciela Reyes Contreras, Francisco Hernandez Rodriguez, Kirsty Marshall, Sharon Jackson, Amy J. Holmes, Peter Ganly, Andrew Butler, Wei‐Hsun Hsu, Sean Macpherson, Emma‐Jane McDonald, Wendy Stewart, Waleed Ghanima, Eiriki Tjonnfjord, Sebastian Grosicki, Ewa Bodzenta, Marek Kriegler, Zofia Spyra‐Gorny, Maria Soroka‐Wojtaszko, Oliwia Bachanek‐Mitura, Justyna Kozinska, Szymon Fornagiel, Beata Kumiega, Grzegorz Basak, Jagoda Rytel, Maciej Kazmierczak, Piotr Cieslak, Emil Durka, Marek Kotlarski, Michal Kwiatek, Justyna Pieronkiewicz, Lukasz Pruchniewski, Teresa Melo, Mafalda Alpoim, Margarida Badoir, Henrique Coelho, Cristina Fereira, Marta Nunes, Sofie Ramalheira, Antonio Medina de Almeida, Paulo Bernardo, Paula Braga, Maria Fátima Ferreira, Pedro Afonso Costa Baptista, Marta Henriques, Celina Afonso, Guadalupe Gomes, Francisca Miranda, Filipa Mousinho, Ana Ramalhal Jorge, Mariana Vasilica, Andra Tomescu, Luminita Ocroteala, Gabriela Diana Baluta, Doriana Duta, Ioan Macarie, Marcela Candea, Georgeta Daniela Georgescu, Lidia Mihai, Florina Patrinoiu, Alina Catana, Alice Dumitrescu, Gabriela Borsaru, Anca Ciobanu, Laura Cristina Predescu, Delia‐Monica Dima, Ana Maria Bancos, Daniela Dragancea, Simona Galdean, Nicoleta Negru, Sergey Zakharov, Yulia Dubinina, Alvetina Lidzhieva, Uruzmag Tomaev, I Pospelova Tatiana, Tatiana Babaeva, Olga Seregina, Svetlana A. Volkova, Elena Kiseleva, Valeria Turetskova, Maria Novikova, Zhanna Davydova, Irina Novokreschenova, Svetlana Valerievna Samarina, Marina Kokoreva, Zorica Cvetkovic, Tamara Bibic, Milica Tanasjievic, Andrew B. McDonald, David Brittain, Philippa Ashmore, Karen Gunther, Johnny Mahlangu, Ching Yu Wang, Vernon Johan Louw, Cecile Du Toit, Elzanne Jansen van Rensburg, Gerdlen Johanna Kritzinger, Perry Loebenberg, Gamuchirai Tadzimirwa, Estelle Verburgh, Blanca Sanchez Gonzalez, Sara Garcia Avila, Yao‐yu Hsieh, Yu‐Sheng Chang, Tsu‐Yi Chao, Wei‐Hong Cheng, Po‐Ya Chuang, Sheng‐Hong Lin, Hui‐Wen Liu, Archrob Khuhapinant, Rarinee Rungjirajittranon, Noppacharn Uaprasert, Chatphatai Moonla, Suporn Chuncharunee, Pichika Chantrathammachart, Teeraya Puavilai, Chatree Chai‐Adisaksopha, Pokpong Piriyakhuntorn, Tontanai Numbenjapon, Wittawat Jandamnernpong, Rattapan Lamool, Nonglak Kanitsap, Lantarima Bhoopat, Nattiya Teawtrakul, Kanchana Chansung, Theerin Lanamtieng, Chinadol Wanitpongpun, Abderrahim Khelif, Bechir Achour, Walid Bouteraa, Raihane Ben Lakhal, Yosr Abdnnebi, Dorra Dhaouadi, Emna Maaloul, Moez Elloumi, Moez Medhaffa, Selami Kocak Toprak, Bulent Karakaya, Ekin Kircali, Gul Yavuz, Filiz Vural, Nigar Abdullayeva, Aysenur Arslan, Ajda Gunes, Fatma Keklik Karadag, Tural Pashayev, Denis Sabriye Bozer, Bahar Sevgili, Nur Soyer, Tuba Hacibekiroglu, Yasin Kalpakci, Cenk Sunu, Fevzi Altuntas, Semih Basci, Merih Kizil Cakar, Sema Secilmis, Mehmet Sinan Dal, Bahar Uncu Ulu, Samet Yaman, Tugce Nur Yigenoglu, Anil Tombak, Fatma Akbas, Meliha Nalcaci, Simge Erdem, Dilek Ozden Kubilay, Tarik Tiryaki, Ozgur Mehtap, Ayfer Geduk, Meltem Ayli, Tuba Bulduk, Alparslan Merdin, Melda Ozkan, Selim Sayin, Bilge Ugur, Murat Yildirim, Ahmet Muzaffer Demir, Ufuk Demirici, Elif Umit, Ahmet Yigitbasi, Burhan Turgut, Seval Akpinar, Mehmet Sonmez, Ozlen Bektas, Nergiz Erkut, Benjamin Bailiff, Salama Abosaod, Rabia Afghan, Amy Gudger, Tsan Hei Luk, Timothy Moorby, Maria Mushkbar, Beena Salhan, Elizabeth Tebbet, Adam Forbes, Michale Creagh, Nicole Fowler, Michelle Furtado, Cristina Maria Thiebaud Alvarez, David Tucker, Martha Vickers, Nichola Cooper, Christine Ademokun, Nehal Joshi, Lucy Kamuriwo, Clare Rees, Steven Lentz, Mark Karwal, Usha Perepu, Grerk Sutamtewagul, Catherine M. Broome, Pedro Alcedo, Julia Cunningham, Graig Kessler, Sunil Babu, Farrukh Adhami, Carrie Boots, Shalini Chitneni, Ryan Gonzales, Yasolatha Nalamolu, Sreenivasa Nattam, Guinevere Nilles, Ahad Sadiq, Shelley Seabolt, David Zimmerman, Bashar Alasad, Loralei Floden, Samer Hassan, Nasser Janbay, Kellie Larsen‐Dyer, Eric S. Schaefer, Joseph Beck, Daniel Bradford, Brooke Brander, Lynsay Brautnick, Mikaila Calcagni, K’Anne Cash‐Arthur, Rita Draggs, Diane Glendinning, Cristina Hernandez, Sarah Jewell, Matthew Lockwood, Gregory Oakhill, Stephan Rosenfeld, Patrick Travis +546 morewiley +1 more sourceAcute Infection and Subsequent Subclinical Reactivation of Herpes Simplex Virus 2 after Vaginal Inoculation of Rhesus Macaques. [PDF]
, 2019 Herpes simplex virus 2 (HSV-2) is a common sexually transmitted infection with a highly variable clinical course. Many infections quickly become subclinical, with episodes of spontaneous virus reactivation.Burgener, Adam, Carroll, Timothy, Corey, Lawrence, Farr Zuend, Christina, Fritts, Linda, Hansen, Scott G, Huang, Meei-Li, Huang, Ying, Koelle, David M, Lo, Ming, Ma, Zhong-Min, Miller, Christopher J, Nöel-Romas, Laura, Picker, Louis J, Sun, Sijie, Zhu, Jia +15 morecore Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Animal Models and Experimental Medicine, EarlyView.Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty +4 morewiley +1 more sourceVaccines against Genital Herpes: Where Are We?
Vaccines, 2020 Genital herpes is a venereal disease caused by herpes simplex virus (HSV). Although HSV symptoms can be reduced with antiviral drugs, there is no cure. Moreover, because HSV infected individuals are often unaware of their infection, it is highly likely ...Hyeon Cheol Kim, Heung Kyu Leedoaj +1 more sourceAntiherpes simplex virus type 2 activity of the antimicrobial peptide subtilosin [PDF]
, 2014 In the present study we evaluated the antiviral activity of subtilosin, a cyclical peptide isolated from Bacillus amyloliquefaciens, against herpes simplex virus type 2 (HSV-2) in cell cultures and we investigated subtilosin mode of action. We determined,Castilla, Viviana, Chikindas, Michael, Quintana, Verónica Mara, Sinko, Patrick J., Torres, Nicolás, Wachsman, Mónica B. +5 morecore +1 more sourceHerpes simplex virus in the human cornea [PDF]
British Journal of Ophthalmology, 2000 Herpes simplex virus (HSV) infection is prevalent throughout the world. An estimated 60–70% of children aged 5 and close to 90% of adults exhibit seropositivity (neutralising antibody) to HSV antigens. Despite this widespread prevalence, only 20%–30% present with clinical disease, and ocular manifestations develop in less than 1%.1 Traditionally, the openaire +1 more source
