Results 111 to 120 of about 8,405,379 (306)

Human herpes virus and Alzheimer’s disease [PDF]

, 2013
Alzheimer’s disease (AD) is a chronic and progressive neurodegenerative disorder and according to the WHO it is estimated that 36 millions of people worldwide currently suffer from AD. Genetic and environmental factors interact in a complex interplay that might affect pathogenic mechanisms leading to age-related neurodegeneration.
openaire   +1 more source

Characterization of murine gammaherpesvirus 68 glycoprotein B (gB) homolog: similarity to Epstein-Barr virus gB (gp110) [PDF]

, 1994
Murine gammaherpesvirus 68 (MHV-68) is a natural pathogen of murid rodents and displays similar pathobiological characteristics to those of the human gammaherpesvirus Epstein-Barr virus (EBV).
Sunil-Chandra, N P, Nash, Anthony, Janjua, N J, Arrand, J R, Stewart, J.P.   +4 more
core  

Special papers Herpes progenitalis – prevention of herpes simplex virus infections

, 2015
Genital herpes is one of the most common sexually transmitted viral diseases and the most common cause of mucosal erosions and ulcerations in the genital area.
Ewelina Biało-Wójcicka, Sławomir Majewski, Katarzyna Łoza   +2 more
core   +1 more source

Herpes Simplex Virus Binds to Human Serum Lipoprotein

Intervirology, 1988
Binding of herpes simplex virus (HSV) type 1 to the various subclasses of human serum lipoproteins was investigated. Studies were performed with human serum lipoproteins purified by differential ultracentrifugation and artificial proteoliposomes containing only one type of apolipoprotein (Al5 E) by using an enzyme-linked immunosorbent assay technique ...
H P, Huemer, H J, Menzel, D, Potratz, B, Brake, D, Falke, G, Utermann, M P, Dierich   +6 more
openaire   +2 more sources

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

Seroprevalence and seroincidence of herpes simplex virus type 1 and herpes simplex virus type 2 infections in a cohort of adolescents in Italy

, 2004
OBJECTIVE: The objective of this study was to improve the knowledge on the epidemiology of herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) in Italy.
PALU', GIORGIO, GRILLI G, SULIGOI B, TORRI A, THE ITALIAN HERPES MANAGEMENT FORUM, TANZI E   +5 more
core   +2 more sources

Successful surgical treatment of hypertrophic genital herpes in HIV-infected patient

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2023
Genital herpes is mostly caused by the herpes simplex virus Type 2 and is frequent in patients infected with the human immunodeficiency virus. In this setting, the disease may have atypical clinical presentations, including an unusual pseudotumoral ...
Fernando M. Gonzaga, Adriana B. Campaner, Giulia Marchetti, Maria A. Longo-Galvão   +3 more
doaj  

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

Interdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang, Baoyuan Zhu, Yuanyuan Huang, Liqin Liang, Zhaobo Li, Yunheng Diao, Minxin Guo, Heng Zhang, Jing Zhou, Fengchun Wu, Kai Wu   +10 more
wiley   +1 more source

Screening of Antiviral Activity of Naturally Occurring Substances Against Herpes Simplex Virus

Антибиотики и Химиотерапия
Background. Herpesviruses are among the most common human pathogens that cause a variety of diseases, including herpetic stomatitis, ophthalmic herpes, genital herpes, chickenpox, and shingles.
A. A. Shtro, A. V. Galochkina, D. O. Pustylnikova, D. N. Razgulyaeva, S. S. Shmeleva, Ia. R. Orshanskaia, K. I. Stosman, O. V. Matusevich, K. V. Sivak   +8 more
doaj   +1 more source