Results 11 to 20 of about 8,405,379 (306)

Herpes simplex virus interferes with amyloid precursor protein processing. [PDF]

open access: yes, 2005
Background The early events underlying Alzheimer's disease (AD) remain uncertain, although environmental factors may be involved. Work in this laboratory has shown that the combination of herpes simplex virus type 1 (HSV1) in brain and carriage of the ...
Shipley, Suzanne J.   +3 more
core   +6 more sources

Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]

open access: yes, 2011
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu   +16 more
core   +1 more source

Herpes simplex virus triggers and then disarms a host antiviral response [PDF]

open access: yes, 2001
Virus infection induces an antiviral response that is predominantly associated with the synthesis and secretion of soluble interferon. Here, we report that herpes simplex virus type 1 virions induce an interferon-independent antiviral state in human ...
Smiley, J R   +5 more
core   +1 more source

Herpes simplex virus type 2: epidemiology and management options in developing countries [PDF]

open access: yes, 2007
Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission is facilitated by the large number of undiagnosed cases, the frequency of atypical ...
Geretti, AM   +7 more
core   +1 more source

Using CSF Proteomics to Investigate Herpesvirus Infections of the Central Nervous System

open access: yesViruses, 2022
Herpesviruses have complex mechanisms enabling infection of the human CNS and evasion of the immune system, allowing for indefinite latency in the host. Herpesvirus infections can cause severe complications of the central nervous system (CNS).
Saima Ahmed   +8 more
doaj   +1 more source

CURRENT CONCEPT OF HUMAN HERPESVIRUS TYPE 6 INFECTION

open access: yesАрхивъ внутренней медицины, 2016
Human herpes virus type 6 infection is widely distributed. It is extensively studied recent years due to the imperfection of diagnostics, as well as participa- tion in the formation of chronic somatic pathology.
E. V. Melehina   +4 more
doaj   +1 more source

Phylogeographic analysis reveals an ancient East African origin of human herpes simplex virus 2 dispersal out-of-Africa

open access: yesNature Communications, 2022
There are competing hypotheses for human herpes simplex virus 2’s migration out-of-Africa. Here, the authors sequence 65 new herpes simplex virus 2 genomes with a focus on under-sampled sub-Saharan African countries, suggesting an Eastern African origin ...
Jennifer L. Havens   +5 more
doaj   +1 more source

On the Issue of Herpes Infection as an Actual Problem Nowadays

open access: yesAktualʹnaâ Infektologiâ, 2016
Among persistent intracellular agents, a group of herpesviruses occupies the leading place after the prevalence. The World Health Organization (WHO) warns the international community of the danger of latent herpes infection pandemic. According to the WHO,
V.P. Borak   +3 more
doaj   +1 more source

Vegetative chronic genital herpes with satisfactory response to imiquimod [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2019
Vegetative chronic genital herpes is an atypical presentation of herpes simplex 2 that it is usually seen in patients coinfected with human immunodeficiency virus.
Stella Meireles Siqueira   +3 more
doaj   +2 more sources

Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. [PDF]

open access: yes, 2007
BACKGROUND: Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS: We conducted a randomized,
Becquart, Pierre   +16 more
core   +1 more source

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