Results 41 to 50 of about 8,817,949 (255)

DIAGNÓSTICO MOLECULAR DE INFECCIÓN POR VIRUS HERPES SIMPLEX TIPO 1 EN TEJIDO ATEROSCLERÓTICO HUMANO

Biociencias, 2018
Introducción: Las enfermedades del sistema circulatorio representan uno de los mayores problemas de salud pública a nivel mundial, nacional y regional. El mecanismo patogénico que subyace esta patología es la aterosclerosis.
Franklin E. Torres J., José Luis Villarreal C   +1 more
doaj   +1 more source

Herpes simplex virus type 2 trends in relation to the HIV epidemic in northern Malawi. [PDF]

, 2008
OBJECTIVES: It is unclear whether the high prevalence of herpes simplex virus type 2 (HSV-2) found in much of Africa predates the HIV epidemic or is, to some extent, a consequence of it.
Fine, P.E.M., Glynn, JR, Glynn, J.R., Mwanyongo, O., Crampin, A.C., Crampin, AC, Ngwira, B.M.M., Ngwira, BMM, Ndhlovu, R., Mwanyongo, O, Fine, PEM, Ndhlovu, R   +11 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Review on Herbal alternatives for the treatment of Herpes zoster infection

Journal of Research in Traditional Medicine, 2021
Background: Herpes viruses are responsible for a variety of mild to severe human diseases, which are sometimes life-threatening, particularly in immunocompromised patients and neonates.
Komal Digambar Madhav, Rajashree Hirlekar   +1 more
doaj   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Kaposi varicelliform eruption caused by varicella virus in a case of tinea corporis et cruris

Clinical Dermatology Review, 2020
Kaposi varicelliform eruption (KVE) is a disseminated vesiculopustular lesion occurring over a preexisting cutaneous lesion. Although initially thought to be caused by herpes virus 1 and 2, other viruses have also been known to provoke the disease. There
Mudita Gupta, Saru Thakur, Reena Kumari Sharma   +2 more
doaj   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Do herpes e suas implicações audiológicas: uma revisao de literatura Herpes and its hearing implications: a literature review

Revista CEFAC, 2009
TEMA: herpes e audiologia. OBJETIVO: realizar revisão teórica principalmente sobre os vírus herpes simples tipo 1, herpes simples tipo 2 e varicela-zoster, bem como sobre seus efeitos na audição humana.
Larissa Cristina Schuster, Ceres Buss
doaj   +1 more source

Population-level effect of potential HSV2 prophylactic vaccines on HIV incidence in sub-Saharan Africa. [PDF]

, 2009
Herpes simplex virus type-2 (HSV2) infection increases HIV transmission. We explore the impact of a potential prophylactic HSV2 vaccination on HIV incidence in Africa using STDSIM an individual-based model.
Orroth, K. K., Buve, A, Weiss, Helen A, Hayes, R. J., Glynn, Judith R, Weiss, H. A., White, Richard G, Hayes, Richard J, Bakker, R., Orroth, Kate K, Buvé, Anne, Freeman, EE, Glynn, J. R., Weiss, HA, White, R. G., Freeman, Esther E, Freeman, E. E., Buvé, A., White, RG, Glynn, JR, Orroth, KK, Bakker, Roel, Hayes, RJ   +22 more
core   +1 more source