Results 221 to 230 of about 8,817,949 (255)

Risk Assessment of an Illegal Laboratory in Reedley, California, Using Geospatial Analysis of Open‐Source Epidemic Intelligence Data

open access: yesRisk Analysis, Volume 46, Issue 11, November 2026.
ABSTRACT An illegal laboratory discovered in Reedley, California, in December 2022 was in a warehouse, operating without a license, handling about a thousand transgenic mice, chemicals, and possibly over 20 pathogens, including vials labeled Ebola, which were never tested but destroyed.
Atalay Goshu Muluneh   +7 more
wiley   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

open access: yesAdvanced Materials Technologies, Volume 11, Issue 20, 21 October 2026.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi   +4 more
wiley   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, Volume 13, Issue 60, 28 October 2026.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

open access: yesAdvanced Science, Volume 13, Issue 59, 23 October 2026.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du   +10 more
wiley   +1 more source

Transport–Reaction–Signal Coupling in Lateral Flow Assays for Next‐Generation Point‐of‐Care Diagnostics

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
Lateral flow assays are evolving into interdisciplinary, system‐level sensing platforms. Recent innovations are deconstructed through coupled phases of mass transfer, reaction, and signal transduction, revealing interdependence across porous materials, interfacial chemistry, nanolabels, readout devices, and data‐enabled analysis.
Yan Pan   +6 more
wiley   +1 more source

Social Behavior in Adult Female Pigtail Macaques (Macaca nemestrina): Evidence for Familiarity‐Independent Pairing Success

open access: yesAmerican Journal of Primatology, Volume 88, Issue 10, October 2026.
Adult female pigtail macaques exhibit social competence and tolerance with a high rate of socialization success and are suitable for continuous pair housing with unfamiliar partners. ABSTRACT This study examined how partner familiarity influences social behavior in pigtail macaques (Macaca nemestrina) housed in continuous full‐contact pairs. Behavioral
Jessica E. Toscano   +3 more
wiley   +1 more source

The right temperature at the right time: A framework for understanding thermoregulatory pathophysiology in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract The neuromodulatory subcortical system (NSS) includes thermoregulatory neurons that maintain core body temperature (Tb) and brain temperature within a narrow, diurnally varying range. Cellular pathways in NSS neurons implicated in Alzheimer's disease (AD) may be vulnerable to Tb rhythm disturbance because of their sensitivity to temperature ...
Esther Blessing
wiley   +1 more source

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