Results 231 to 240 of about 8,817,949 (255)

ApoE lipidation state directs immunometabolic reprogramming of human microglia

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION ApoE ε4 is the strongest genetic risk factor for Alzheimer's disease (AD). Emerging evidence suggests that ApoE4 increases AD risk by disrupting microglial metabolism and function. However, whether ApoE lipidation state contributes to microglial dysfunction remains poorly understood. METHODS Human microglia were treated with lipid‐
Tsion G. Shiferaw, Snigdha Sarkar, Katelyn M. Baker, Rowan S. Wooldridge, Hannah M. Binfet, Victoria N. Prozapas, Chinemerem P. Ogbu, Athena A. Schepmoes, Isaac K. Attah, Christy S. Niemeyer, Kayla G. Sprenger, James E. Hassell, Robert H. Eckel, John T. Melchior, Kimberley D. Bruce   +14 more
wiley   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2149-2159, October 2026.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Perfusion Cell Cultures: Is the Technology Worthwhile for Biopharmaceutical Production?

ChemBioEng Reviews, Volume 13, Issue 5, October 2026.
The biotechnology industry is pursuing innovation and robust production, yet many biopharmaceuticals are manufactured from batch or fed‐batch cell cultures. Perfusion processes, offering higher yields and efficiency, remain underused despite their maturity.
Francesco Iannacci, Mattia Sponchioni
wiley   +1 more source

Overview on Epstein–Barr Virus–Host Interactions With a Focus on Host Cell Transcriptome Alterations

Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT The Epstein–Barr virus (EBV) belongs to the gamma subgroup of human herpesviruses. EBV is particularly lymphotropic regarding its latency, meaning that it preferentially targets lymphocytes as its immunological niche. During the establishment of the complex virus–host relationships, the virus influences the human host cell transcriptome ...
Louise Wallot, Tim Hohmann, Urszula Hohmann, Faramarz Dehghani, Olaf Grisk, Simon Jasinski‐Bergner   +5 more
wiley   +1 more source

Severe Pediatric MOGAD‐Associated ADEM With Persistent Neurological Morbidity and Later‐Onset Epilepsy of Uncertain Etiology: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This report describes a 7‐year‐old boy with MOGAD presenting as severe ADEM with fever, encephalopathy, seizures, markedly elevated intracranial pressure, diffuse multifocal MRI abnormalities, and serum MOG‐IgG positivity. He required intravenous corticosteroids, plasma exchange, IVIG, and tocilizumab, followed by rehabilitation and ...
Desiree‐Anne Ramsaran, Garrett Gianneschi, Janet Elgallab   +2 more
wiley   +1 more source

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Vikrant V Sahasrabuddhe, Philip E Castle, Mark H Einstein   +2 more
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Viruses and human cancer

Ca-A Cancer Journal for Clinicians, 1973
D W Allen, Philip Cole, David W Allen
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Pathogenesis and virulence of herpes simplex virus

Virulence, 2021
Abel Viejo-Borbolla
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Frontiers in Neuroscience, 2023
Weihong Xu, Chunfu Zheng, Yuchao Chen
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