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Human Herpesvirus 6 and Malignancy: A Review [PDF]
In order to determine the role of human herpesvirus 6 (HHV-6) in human disease, several confounding factors, including methods of detection, types of controls, and the ubiquitous nature of the virus, must be considered. This is particularly problematic in the case of cancer, in which rates of detection vary greatly among studies. To determine what part,
Eva Eliassen+9 more
doaj +8 more sources
Endogenization and excision of human herpesvirus 6 in human genomes
Sequences homologous to human herpesvirus 6 (HHV-6) are integrated within the nuclear genome of about 1% of humans, but it is not clear how this came about. It is also uncertain whether integrated HHV-6 can reactive into an infectious virus. HHV-6 integrates into telomeres, and this has recently been associated with polymorphisms affecting MOV10L1 ...
Xiaoxi Liu+22 more
doaj +6 more sources
Human Herpesvirus 6: An Emerging Pathogen [PDF]
Infections with human herpesvirus 6 (HHV-6), a beta-herpesvirus of which two variant groups (A and B) are recognized, is very common, approaching 100% in seroprevalence. Primary infection with HHV-6B causes roseola infantum or exanthem subitum, a common childhood disease that resolves spontaneously.
Campadelli-Fiume G.+2 more
doaj +5 more sources
Human Herpesvirus 6 Encephalomyelitis
To the Editor: Denes et al. (1) reports successful treatment of human herpesvirus 6 (HHV-6) encephalomyelitis. The patient was an immunocompetent young woman whose symptoms were fever, urinary retention, blurred vision, quadriparesis, bilateral papillitis, and optic neuritis.
Jose Luis Soto-Hernandez+2 more
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β-HHVs and HHV-8 in Lymphoproliferative Disorders. [PDF]
Similarly to Epstein-Barr virus (EBV), the human herpesvirus-8 (HHV-8) is a γ-herpesvirus, recently recognized to be associated with the occurrence of rare B cell lymphomas and atypical lymphoproliferations, especially in the human immunodeficiency virus
BAROZZI, Patrizia+7 more
core +4 more sources
Human Herpesvirus-6 and Roseola Infantum Meningitis [PDF]
Two infants with roseola infantum and meningitis caused by human herpesvirus-6 infection are reported from the Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
J Gordon Millichap
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Background. Human herpesvirus 6 belongs to betaherpesviruses. This is a lymphotropic virus which is widely spread in a population. The most frequent way of virus transmission is by saliva. For this reason the first contact usally occurs early in a childhood period. Clinical manifestation might be expressed as exanthem subitum or roseola infantum.
Jožica Marin
openaire +4 more sources
Animal models for human herpesvirus 6 infection [PDF]
Human herpesvirus (HHV)-6A and HHV-6B are two enveloped DNA viruses of β-herpesvirus family, infecting over 90% of the population and associated with several diseases, including exanthema subitum (for HHV-6B), multiple sclerosis and encephalitis, particularly in immunosuppressed patients.
Reynaud, Joséphine M, Horvat, Branka
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Latency, Integration, and Reactivation of Human Herpesvirus-6
Human herpesvirus-6A (HHV-6A) and human herpesvirus-6B (HHV-6B) are two closely related viruses that infect T-cells. Both HHV-6A and HHV-6B possess telomere-like repeats at the terminal regions of their genomes that facilitate latency by integration into
Shara N. Pantry, Peter G. Medveczky
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Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6
Background Human herpesvirus-6A and -6B (HHV-6) are betaherpesviruses that reach > 90% seroprevalence in the adult population. Unique among human herpesviruses, HHV-6 can integrate into the subtelomeric regions of human chromosomes; when this occurs in ...
Alexander L. Greninger+19 more
doaj +2 more sources