Results 111 to 120 of about 8,383,878 (290)

Human herpesvirus latency and fatigue

open access: yesUirusu, 2005
Human herpesvirus (HHV)-6 and HHV-7 establish life-long latency, a hallmark of herpesviruses, reactivate frequently, and are shed in saliva. To investigate the viral reactivation, we have identified the latency-associated transcripts of HHV-6, and have revealed the partial mechanism of HHV-6 reactivation.
openaire   +4 more sources

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

open access: yesCell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far   +4 more
wiley   +1 more source

Parvovirus B19‐associated myocarditis in children: A systematic review of clinical features, management and outcomes

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This systematic review summarizes clinical features, diagnostic strategies and outcomes of paediatric myocarditis associated with Parvovirus B19. Affected children are typically under 3 years old and often present with fulminant symptoms, severe cardiac dysfunction and a high need for ICU‐level support or mechanical circulatory assistance.
Giacomo Veronese   +5 more
wiley   +1 more source

Acute neurologic presentation of a 2‐year‐old standardbred colt with multicentric diffuse large B cell lymphoma

open access: yesEquine Veterinary Education, EarlyView.
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan   +3 more
wiley   +1 more source

Can Unilateral Pityriasis Rosea be Considered a Form of Superimposed Lateralized Exanthem? [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Francesco Drago   +2 more
doaj   +1 more source

Pityriasis Rosea in a Pregnancy

open access: yesGynecology Obstetrics & Reproductive Medicine, 2012
A pregnant woman with Pitriasis rosea whose lesion onset is in first trimester is presented. No interventions were undertaken and her eruption remitted completely 6-7 weeks. We found no evidence of active infection for HHV-6 and HHV-7.
Abdullah Karaer   +2 more
doaj  

A guide to heat shock factors as multifunctional transcriptional regulators

open access: yesThe FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka   +3 more
wiley   +1 more source

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