Results 121 to 130 of about 627,562 (273)
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri +13 more
wiley +1 more source
Partial characterisation of pilchard herpesvirus and the associated disease in pilchards
In 1995 and again in 1998, millions of pilchards (Sardinops sagax neopilchardus) were found dead or dying off the coast of Australia and also in New Zealand. The epizootics moved progressively, at a rapid speed against the prevailing currents.
Crockford, Melanie
core
Transmission of human herpesvirus 8: An update
PURPOSE OF REVIEW: Human herpesvirus 8 is associated with neoplastic diseases in the immunocompromised host, including Kaposi's sarcoma, multicentric Castleman disease and primary effusion lymphoma.
PICA, FRANCESCA +3 more
core +1 more source
Human herpesvirus latency and fatigue
Human herpesvirus (HHV)-6 and HHV-7 establish life-long latency, a hallmark of herpesviruses, reactivate frequently, and are shed in saliva. To investigate the viral reactivation, we have identified the latency-associated transcripts of HHV-6, and have revealed the partial mechanism of HHV-6 reactivation.
openaire +3 more sources
Herpesvirus-host interactions in neurological diseases: the immunogenetic role of HLA-E
Human herpesviruses (HHVs) comprise nine pathogenic members, including herpes simplex virus 1, herpes simplex virus 2, varicella-zoster virus, Epstein–Barr virus, human cytomegalovirus, human herpesvirus 6A/B, human herpesvirus 7, and Kaposi’s sarcoma ...
Marianne Graninger +2 more
doaj +1 more source
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique +6 more
wiley +1 more source
R17 Drives Heparan Sulfate Clearance via Endolysosomal Trafficking
R17 is a viral protein that binds heparan sulfate glycosaminoglycans and traffics them to the lysosome, leading to their degradation in a manner that does not require the presence of the cation‐independent mannose‐6‐phosphatre receptor. In BxPC3 pancreatic cancer cells, this loss in heparan sulfate results in the reduction of cell migration.
Pranali Bedekar +7 more
wiley +1 more source
Herpesviruses are ubiquitous double-stranded DNA viruses infecting many animals, with the capacity to cause disease in both immunocompetent and immunocompromised hosts.
Charlotte J. Houldcroft +3 more
core +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Role of the human beta-herpesviruses in organ allograft rejection following transplantation.
In previous prospective studies conducted in our department, PCR was used to detect the three ({dollar}-herpesviruses, human cytomegalovirus (HCMV), and human herpesviruses 6 and 7 (HHV-6 and HHV-7) in the blood of solid organ transplant patients.
Li, Y.T., Li, Yingting
core

