Results 121 to 130 of about 387 (176)

Deciphering the full spectrum of Castleman diseases based on a cohort of 700 patients in a western country

British Journal of Haematology, Volume 208, Issue 6, Page 2036-2046, June 2026.
The spectrum of Castleman diseases has expanded over the past three decades. The phenotype of the diseases varies not only among the three major types but also according to the patient ancestry. Summary Under the Castleman disease (CD) eponym, three distinct diseases sharing common pathological features have been described over time.
Eric Oksenhendler, Marion Malphettes, Véronique Meignin, David Boutboul, Lionel Galicier   +4 more
wiley   +1 more source

Human Herpesvirus-8 Immediate-Early Region-4 Gene Locus [PDF]

, 2020
openaire   +1 more source

Repurposing Purine Analog Antivirals to Modulate Serum Uric Acid: Evidence From Real‐World Data

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Xanthine oxidase (XO) inhibitors remain the standard pharmacologic therapy for hyperuricemia. However, additional enzymatic components of the purine degradation pathway may contribute to uric acid synthesis. Guanine deaminase (GD) catalyzes the conversion of guanine to xanthine, providing substrate for downstream oxidation by XO.
Joseph Magagnoli, Tammy H. Cummings, Michael D. Wyatt, Campbell McInnes, Jayakrishna Ambati, S. Scott Sutton   +5 more
wiley   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
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HemaSphere, Volume 10, Issue S1, June 2026.
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Natural antibody–complement dependent neutralization of bovine herpesvirus 4 by human serum

Microbes and Infection, 2007
In contrast to most gammaherpesviruses, Bovine herpesvirus 4 (BoHV-4) has a broad range of host species both in vitro and in vivo. Several in vitro studies demonstrated that some human cell lines are sensitive or even permissive to BoHV-4. These observations led to the hypothesis that cross-species transmission of BoHV-4 could lead to human infections.
Machiels, Bénédicte, Gillet, Laurent, Brito, Sieberth Do Nascimento, Drion, Pierre, Delforge, Cédric, Nizet, Yannick, Gianello, Pierre, Bona, Christophe, Costes, Bérénice, Markine-Goriaynoff, Nicolas, Vanderplasschen, Alain   +10 more
openaire   +2 more sources

Serological study of human herpesvirus simplex 1 and bovine herpesvirus 1, 2, and 4 in Kansas cattle

The Bovine Practitioner, 1989
A total of 589 beef cattle and 466 dairy cattle were tested for antibodies to herpes simplex virus-1 (HSV-1) and bovine herpes virus-1, 2, and 4 (BHV) using the indirect fluorescent antibody test (IFAT). In the beef cattle, prevalence of antibodies to HSV-1, BHV-1, 2, and 4 was 34.8%, 67.9%, 36.5% and 12.4% respectively, and in the dairy cattle ...
Phillips, R. M., Nassar, R. F.
openaire   +1 more source

4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as Non-Nucleoside Inhibitors of Human Cytomegalovirus and Related Herpesvirus Polymerases

Journal of Medicinal Chemistry, 2005
A novel series of 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potential antivirals against human herpesvirus infections resulting from human cytomegalovirus (HCMV), herpes simplex virus type 1 (HSV-1), and varicella-zoster virus (VZV).
Mark E, Schnute, Michele M, Cudahy, Roger J, Brideau, Fred L, Homa, Todd A, Hopkins, Mary L, Knechtel, Nancee L, Oien, Thomas W, Pitts, Roger A, Poorman, Michael W, Wathen, Janet L, Wieber   +10 more
openaire   +2 more sources

Modulation of CD4, CXCR-4, and CCR-5 Makes Human Hematopoietic Progenitor Cell Lines Infected with Human Herpesvirus-6 Susceptible to Human Immunodeficiency Virus Type 1

Journal of Hematotherapy & Stem Cell Research, 2000
Two CD34+ human hematopoietic progenitor cell (HPC) lines, KG-1 and TF-1, became susceptible to human immunodeficiency virus type 1 (HIV-1) infection in the presence of a concurrent infection by human herpesvirus-6 (HHV-6). We have analyzed the possible mechanism(s) underlying this phenomenon in light of the recent demonstration that at least two ...
M, Vignoli, G, Furlini, M C, Re, E, Ramazzotti, M, La Placa   +4 more
openaire   +2 more sources

Detection and Analysis of Protein‐Protein Interactions between KU70 and BHRF1, a BCL2 viral analog within Human gamma herpesvirus 4

The FASEB Journal, 2020
The Epstein‐Barr virus, also known as human gamma herpesvirus 4 (HHV‐4), affects more than 90% of the adult human population worldwide. To prevent premature death of the host cell, HHV‐4 encodes for BHRF1, an anti‐apoptotic protein with sequence and structural similarities to other proteins involved in apoptosis such as BCL2, BAX and BAK, among others.
Sheighlah McManus, Alexander Emami, Alberto Zamora   +2 more
openaire   +1 more source