Results 141 to 150 of about 89,995,705 (214)

Human herpesvirus 6 and human herpesvirus 7 in chronic fatigue syndrome

open access: yes, 1995
We analyzed lymphocytes of patients with chronic fatigue syndrome (CFS) for the presence of human herpesvirus 6 (HHV-6) and HHV-7 DNA. HHV-7 was present in over 80% of CFS patients and healthy controls, while the prevalence of HHV-6 variant A ...
CASSAI E.   +11 more
core  

Emerging Paediatric Uses of Dupilumab Beyond Approvals

open access: yesClinical &Experimental Allergy, Volume 56, Issue 10, Page 1162-1176, October 2026.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese   +11 more
wiley   +1 more source

Diagnosis and Management of Infectious Encephalitis in Adults: Guidelines From the European Academy of Neurology and European Society of Clinical Microbiology and Infectious Diseases

open access: yesEuropean Journal of Neurology, Volume 33, Issue 10, October 2026.
ABSTRACT Background Encephalitis is difficult to diagnose and manage, posing a challenge to clinicians. Since the last European guidelines were published in 2010, novel causes have emerged, diagnostic processes have evolved and treatments assessed which need to be reflected in updated guidelines.
Julia Granerod   +29 more
wiley   +1 more source

Outcomes of Kaposi sarcoma in people living with HIV who maintain long‐term viral suppression: A prospective case‐series

open access: yesHIV Medicine, Volume 27, Issue 10, Page 1715-1721, October 2026.
Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart   +10 more
wiley   +1 more source

Non-canonical regulation of the reactivation of an oncogenic herpesvirus by the OTUD4-USP7 deubiquitinases.

open access: yesPLoS Pathogens
Deubiquitinases (DUBs) remove ubiquitin from substrates and play crucial roles in diverse biological processes. However, our understanding of deubiquitination in viral replication remains limited. Employing an oncogenic human herpesvirus Kaposi's sarcoma-
Shaowei Wang   +14 more
doaj   +1 more source

Entering the Age of Specificity in T Cell Immunity

open access: yesImmunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT The discovery of MHC restriction, the resolution of peptide–MHC structure, and the identification of the T cell receptor gene quickly centered epitope‐level specificity as a core concern of T cell biology. Epitope mapping culminated in functional peptide‐based stimulation assays and tetramer staining, which together provide exquisite ...
Paul G. Thomas
wiley   +1 more source

HUMAN HERPESVIRUS-8 IN HEMATOLOGICAL DISEASES

open access: yes, 1998
The huge amount of experimental and clinical observations supporting the possible involvement of human herpesvirus 8 (HHV-8) or Kaposi sarcoma herpesvirus (KSHV) in human lymphoproliferative diseases was critically reviewed during a workshop organized by
GAIDANO, Gianluca, TORELLI G.
core  

Understanding the Immune Response Changes to Clinical Interventions for Epstein–Barr Virus Infection Prior to Lymphoma Development in Children After Organ Transplants (UNEARTH)

open access: yesPediatric Transplantation, Volume 30, Issue 10, October 2026.
The T cell and Natural Killer cell immune responses in primary EBV infection in children or during progression to PTLD are not well characterized. By performing detailed prospective immunological phenotyping through the first year after 278 pediatric organ transplants, we will unearth pathways that may inform EBV oncogenesis progression.
Vikas R. Dharnidharka   +22 more
wiley   +1 more source

Clinical and Diagnostic Insights into Penile Angiolymphoid Hyperplasia with Eosinophilia Based on a Case and Analysis of Previous Literature

open access: yesSkin Research and Technology, Volume 32, Issue 10, October 2026.
ABSTRACT Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign vascular proliferation of unknown origin. It typically occurs in the head and neck region, but can occasionally manifest in unusual locations, such as the penis. Herein, we report a case of ALHE in a 46‐year‐old HIV‐infected male presenting with multiple pruritic whitish ...
Rievanda Ayu Natasya   +5 more
wiley   +1 more source

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