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Dendritic cells: Key players in human herpesvirus 8 infection and pathogenesis
Human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) is an oncogenic gammaherpesvirus that primarily infects cells of the immune and vascular systems.
Diana M. Campbell+5 more
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Human herpesvirus 8 seropositivity among sexually active adults in Uganda.
IntroductionSexual transmission of human herpesvirus 8 (HHV8) has been implicated among homosexual men, but the evidence for sexual transmission among heterosexual individuals is controversial. We investigated the role of sexual transmission of HHV8 in a
Fatma M Shebl+9 more
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Human Herpesvirus 8 Genotype E in Patients with Kaposi Sarcoma, Peru
To determine human herpesvirus 8 (HHV-8) K1 genotypes in patients with Kaposi sarcoma (KS) from Peru, we characterized HHV-8 in 25 KS biopsy samples.
Olivier Cassar+9 more
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Human Herpesvirus 8 Seroprevalence in Sardinia [PDF]
Diego Serraino+5 more
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Molecular Detection of Human Herpesvirus-8 in Plasma and Peripheral Blood Mononuclear Cells of Patients with Cryptogenic Cirrhosis [PDF]
Background: Human herpesvirus-8 is the infectious etiology of endothelial origin in tumours with blood disorders. However, in some cirrhotic patients, no etiology can be identified, and such cases are known as cryptogenic cirrhosis. The aim of this study
Farah Bokharaei-Salim+5 more
doaj +1 more source
Angiosarcoma in HIV-negative patients is not associated with HHV-8 [PDF]
: BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as ...
João Avancini+8 more
doaj +2 more sources
Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy
Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona+6 more
doaj +1 more source
E3 Ubiquitin Ligases in Gammaherpesviruses and HIV: A Review of Virus Adaptation and Exploitation
For productive infection and replication to occur, viruses must control cellular machinery and counteract restriction factors and antiviral proteins.
Jessica Oswald+5 more
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Case for diagnosis. Penile lesion in HIV-negative patient, [PDF]
We present the case of an HIV-negative man with asymptomatic penile erythematoviolaceous papules associated with similar slightly verrucous papules in the interdigital space of the right foot. A biopsy of the penile lesion confirmed Kaposi's sarcoma.
Mauro Cunha Ramos+3 more
doaj +1 more source